Effect of Nanohexaconazole on Nitrogen Fixing Blue Green Algae and Bacteria

Kumar, Rajesh; Gopal, Madhuban; Pabbi, Sunil; Paul, Sangeeta; Alam, Md. Imteyaz; Yadav, Saurabh; Nair, Kishore Kumar; Chauhan, Neetu; Srivastava, Chitra; Gogoi, Robin; Singh, P. P.; Goswami, Arunava

doi:10.1166/jnn.2016.10901

Cited by 12 publications

(8 citation statements)

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“…The enhanced bioactivity of nanoproducts can be attributed to their superior inhibition 31 of the target enzyme in comparison to the conventional counterparts. This nanofungicide did not have any negative impact 14,63,70 on soil health, soil nitrifiers, and nitrogen fixers.…”

Section: ■ Results and Discussionmentioning

confidence: 88%

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Preparation of Nanofungicides Based on Imidazole Drugs and Their Antifungal Evaluation

Tippannanavar

Verma

Kumar

et al. 2020

J. Agric. Food Chem.

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In spite of modern crop protection measures, the overall crop losses due to pests and pathogens are huge. Rhizoctonia solani, Macrophomina phaseolina, Sclerotium rolfsii, and Fusarium oxysporum are one of the most devastating soil-borne fungi and cause numerous plant diseases. Therefore, the present study aimed to systematically design and develop new nanofungicides based on imidazole drugs, clotrimazole, econazole nitrate, and miconazole nitrate, for effective and efficient management of plant diseases. The assessment of these antifungal medicines for their fungicide likeness using Hao’s rule and their enzyme inhibitory potential by molecular docking was helpful in ensuring their utility as antifungal agents in managing phytopathogenic fungi. Nanotechnological strategies were used to develop nanoformulations of test compounds in poly(ethylene glycol) 300 for further augmenting their bioactivity. Transmission electron microscopy studies confirmed the nanosize of the prepared products. Analysis of their in vitro and in vivo antifungal properties revealed their usefulness in controlling the test fungi, R. solani, M. phaseolina, S. rolfsii, and F. oxysporum. Excellent in vitro antifungal activities were displayed by the clotrimazole nanoformulation with a median effective dose (ED50) of 1.18 μg/mL against R. solani, the econazole nitrate nanoformulation with an ED50 of 5.25 μg/mL against S. rolfsii, and the miconazole nitrate nanoformulation with an ED50 of 1.49 and 1.82 μg/mL against M. phaseolina and F. oxysporum. Furthermore, in vivo studies against test fungi demonstrated the antifungal potency of all the nanoformulations with disease incidences ranging from 11.11 to 27.38% in plants treated with nanoformulations of test chemicals as compared to the inoculated control (39.68–72.38%).

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Section: ■ Results and Discussionmentioning

confidence: 88%

“…To determine the antifungal potential of these imidazole medicines and the benefits associated with nanotechnological interventions, − the present research was undertaken to develop nanoformulations of clotrimazole, econazole nitrate, and miconazole nitrate for the management of harmful phytopathogens, R. solani, S.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Nanofungicides Based on Imidazole Drugs and Their Antifungal Evaluation

Tippannanavar

Verma

Kumar

et al. 2020

J. Agric. Food Chem.

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“…In addition to affecting photosynthesis, MNMs would affect the algal nitrogen fixation ability (Cherchi and Gu, 2010;Kumar et al, 2016). After exposure to nano-TiO 2 , both the occurrence and intracellular levels of the nitrogen-rich cyanophycin grana proteins (CGPs) in cyanobacteria Anabaena variabilis increased with the increasing concentration and time of nano-TiO 2 exposure, indicating inhabitation in nitrogen fixation activity (Cherchi and Gu, 2010).…”

Section: Mnms Affect Algae's Photosynthesis and Nitrogen Fixationmentioning

confidence: 99%

“…After exposure to nano-TiO 2 , both the occurrence and intracellular levels of the nitrogen-rich cyanophycin grana proteins (CGPs) in cyanobacteria Anabaena variabilis increased with the increasing concentration and time of nano-TiO 2 exposure, indicating inhabitation in nitrogen fixation activity (Cherchi and Gu, 2010). Likewise, it was reported that nano-hexaconazole, a nanoscale polymer carrier for pesticides, caused inhibition in blue-green algae's activity of nitrogen assimilating enzymes (Kumar et al, 2016).…”

Section: Mnms Affect Algae's Photosynthesis and Nitrogen Fixationmentioning

confidence: 99%

Effects of manufactured nanomaterials on algae: Implications and applications

Huang

Gao

Wang

et al. 2022

Front. Environ. Sci. Eng.

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The wide application of manufactured nanomaterials (MNMs) has resulted in the inevitable release of MNMs into the aquatic environment along their life cycle. As the primary producer in aquatic ecosystems, algae play a critical role in maintaining the balance of ecosystems’ energy flow, material circulation and information transmission. Thus, thoroughly understanding the biological effects of MNMs on algae as well as the underlying mechanisms is of vital importance. We conducted a comprehensive review on both positive and negative effects of MNMs on algae and thoroughly discussed the underlying mechanisms. In general, exposure to MNMs may adversely affect algae’s gene expression, metabolites, photosynthesis, nitrogen fixation and growth rate. The major mechanisms of MNMs-induced inhibition are attributed to oxidative stress, mechanical damages, released metal ions and light-shielding effects. Meanwhile, the rational application of MNMs-algae interactions would promote valuable bioactive substances production as well as control biological and chemical pollutants. Our review could provide a better understanding of the biological effects of MNMs on algae and narrow the knowledge gaps on the underlying mechanisms. It would shed light on the investigation of environmental implications and applications of MNMs-algae interactions and meet the increasing demand for sustainable nanotechnology development.

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“…Characteristic feature of this developed formulation is biosafety aspect, and after application of nano-hexaconazole, no impact was observed on soil nitrifiers such as blue green algae and cynobacteria species. Therefore, nano-formulations maintain the sustainable soil fertility and productivity compared with conventional formulations [35].…”

Section: Nanoemulsion Formulationmentioning

confidence: 99%

Vital Role of IPFT in Development of New-Generation Pesticide Formulation for Crop Protection: Advancement Overview in Asian Countries

Iqbal¹,

Agrawal²,

Alam³

et al. 2022

Agricultural Development in Asia - Potential Use of Nano-Materials and Nano-Technology

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The agricultural sector of Asian countries supports 60% of the global population, accounting one-fifth of the world’s agricultural land. Despite the gap between demand and supply of food is gradually increasing due to the damages caused by insect and other pest attacks on the limited agricultural land, the pest attack has influenced the entire agriculture sector either directly or indirectly, causing socioeconomic losses. To combat, farmers have been using conventional agrochemicals nonjudiciously that lead to adverse effects such as pesticide resistance, environmental contamination, and non-target toxicity. In this regard, new-generation agrochemical formulation techniques are advantageous over conventional pesticides and play a vital role in sustainable agriculture by fulfilling the demand of over-rising food supply to feed the increasing population. These formulations exhibit desired bio-efficacy at lower doses and have minimum possibility to leave pesticide residues in crop products and the environment. Institute of Pesticide Formulation Technology (IPFT), Gurugram, is one of the leading institutes in Asia, which is actively engaged in developing new-generation formulations to deliver safer, efficient, and environment-friendly pesticide formulations. So far, IPFT has developed 60 pesticide formulations and transferred technologies to different agrochemical industries globally. The new-generation formulations developed by IPFT mainly include microemulsion, nanoemulsion, capsulated suspension, nano-encapsulation, an emulsion in water, mixed formulations including several botanical pesticide formulations. The new advancement in pesticide delivery systems is very supportive in combating the crisis faced by the agricultural sector. In this chapter, formulation of different new-generation pesticides and their advancement are summarized.

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Effect of Nanohexaconazole on Nitrogen Fixing Blue Green Algae and Bacteria

Cited by 12 publications

References 0 publications

Preparation of Nanofungicides Based on Imidazole Drugs and Their Antifungal Evaluation

Preparation of Nanofungicides Based on Imidazole Drugs and Their Antifungal Evaluation

Effects of manufactured nanomaterials on algae: Implications and applications

Vital Role of IPFT in Development of New-Generation Pesticide Formulation for Crop Protection: Advancement Overview in Asian Countries

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