Effect of linear surface-charge non-uniformities on the electrokinetic ionic-current rectification in conical nanopores

Qian, Shizhi; Joo, Sang Woo; Ai, Ye; Cheney, Marcos A.; Hou, Wensheng

doi:10.1016/j.jcis.2008.10.012

Cited by 50 publications

(38 citation statements)

References 45 publications

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“…4. Details about the implementation and validation of the PNP-NS numerical model have been described in our previous papers [47][48][49][50][51]. The validity of the PNP-NS numerical model is also verified by the quantitative agreement between the analytical solution and the numerical results when ja > 1, as shown in Fig.…”

Section: Theoretical Analysismentioning

confidence: 65%

A low-voltage nano-porous electroosmotic pump

Yalcin

et al. 2010

Journal of Colloid and Interface Science

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Section: Theoretical Analysismentioning

confidence: 65%

A low-voltage nano-porous electroosmotic pump

Yalcin

et al. 2010

Journal of Colloid and Interface Science

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“…The floating electrode is not electrically excited which is in contrast to the gate electrode employed in our previous field effect control of DNA translocation through a nanopore. A multi-ion model (MIM) composed of the coupled Poisson-NernstPlanck (PNP) equations for the ionic mass transport and the Mingkan Zhang 1 modified Stokes equations for the flow field have been employed to study the ionic current rectification in a nanopore [31][32][33]. The results show good agreements with the experiment data.…”

Section: Introductionmentioning

confidence: 86%

“…The numerical simulation of DNA translocation is implemented by solving the electric field, the ionic [31][32][33]36]; while the fluid flow is governed by the modified Stokes equations as the inertial terms are negligible due to a very small Reynolds number in this study. The governing equations are normalized based on the bulk concentration c 0 as the ionic concentration scale, f 0 5 R U T/F as the potential scale, the particle radius a as the length scale, u 0 ¼ eR…”

Section: Mathematical Modelmentioning

confidence: 99%

Electrokinetic particle translocation through a nanopore containing a floating electrode

Zhang

Sharma

et al. 2011

Electrophoresis

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Electrokinetic particle translocation through a nanopore containing a floating electrode is investigated by solving a continuum model, composed of the coupled Poisson-Nernst-Planck (PNP) equations for the ionic mass transport and the modified Stokes equations for the flow field. Two effects due to the presence of the floating electrode, the induced-charge electroosmosis (ICEO) and the particle-floating electrode electrostatic interaction, could significantly affect the electrokinetic mobility of DNA nanoparticles. When the electrical double layers (EDLs) of the DNA nanoparticle and the floating electrode are not overlapped, the particle-floating electrode electrostatic interaction becomes negligible. As a result, the DNA nanoparticle could be trapped near the floating electrode arising from the induced-charge electroosmosis when the applied electric field is relatively high. The presence of the floating electrode attracts more ions inside the nanopore resulting in an increase in the ionic current flowing through the nanopore; however, it has a limited effect on the deviation of the current from its base current when the particle is far from the pore.

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“…Meanwhile, the effects of the geometric nanopores on an ionic current have been studied. The electric field inside the pore will be different when the pore has a different geometry [101][102][103][104].…”

Section: Recent Advancesmentioning

confidence: 99%

Fabrications, Applications and Challenges of Solid-State Nanopores: A Mini Review

Tang

Zhang

Cui

et al. 2016

Nanomaterials and Nanotechnology

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Nanopore sensors are expected to be one of the most promising next generation sequencing technologies, with label-free, amplification-free and high-throughput features, as well as rapid detections and low cost. Solid-state nanopores have been widely explored due to their diverse fabrication methods and CMOS compatibility. Here, we highlight the fabrication methods of solid-state nanopores, including the direct opening and the tuning methods. In addition, molecular translocation developments, DNA sequencing and protein detections are summarized. Finally, the latest progress relating to solid-state nanopores is discussed, which helps to offer a comprehensive understanding of the current situation for solid-state nanopore sensors.

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Effect of linear surface-charge non-uniformities on the electrokinetic ionic-current rectification in conical nanopores

Cited by 50 publications

References 45 publications

A low-voltage nano-porous electroosmotic pump

A low-voltage nano-porous electroosmotic pump

Electrokinetic particle translocation through a nanopore containing a floating electrode

Fabrications, Applications and Challenges of Solid-State Nanopores: A Mini Review

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