Effect of Ischemic Preconditioning on Lactate Accumulation and Running Performance

Abstract

IPC improves 5-km time trial performance in healthy male individuals. Moreover, we found that IPC is associated with an attenuated rise in blood lactate concentration at submaximal level during an incremental running test. This could indicate that IPC allows for higher work rates and thus improves time trial performance.

Ischaemic preconditioning does not alter the determinants of endurance running performance in the heat

“…Each leg was exposed to 5 min of occlusion with the cuff inflated to 220 mmHg (IP) or 50 mmHg (CON), followed by 5 min of reperfusion and rest for 4 consecutive cycles, as has previously been shown to be effective (Jean-St-Michel et al 2011;Bailey, Jones, et al 2012). An overview of the preconditioning protocol and subsequent graded exercise test (GXT) is shown in Figure 1.…”

“…Few studies have considered endurance running, however Bailey, Jones, et al (2012) reported lower blood lactate concentration (mean difference -1.07 mMol.L -1 ) throughout an incremental submaximal running test, although no subsequent effect on maximum oxygen consumption (V" O 2max ) was observed. This was followed by improved 5 km running time with a mean improvement of 34 s (2.5%, p=0.03), highlighting the potential for use prior to endurance running.…”

“…Clevidence et al (2012) speculated that IP appears to be effective when an ischaemic event is most likely and may require a minimum metabolic stress to be achieved during the exercise bout to be effective during exercise. Thus, extreme environmental conditions, higher intensity exercise (Crisafulli et al 2011) and/or activities such as running (Bailey, Jones, et al 2012) and swimming (Jean-St-Michel et al 2011), that elicit significant physiological strain, warrant investigation.…”

“…These markers help determine endurance performance, when combined with running economy (Bassett & Howley 2000). These changes are significant given that the lactate turnpoint (LTP) remains a strong predictor of time trial performance in hot environments (Lorenzo et al 2011) and appears sensitive to the effects of IP (Bailey, Jones, et al 2012), whilst V" O 2max is considered the best individual predictor of performance, explaining 90.2% of the total variance in a 16-km run (McLaughlin et al 2010). Furthermore, evidence exists that occlusion may modify thermoregulatory responses, through the muscle metaboreflex, independently of body temperature (Kondo et al 1999 (James et al 2015;Randall et al 2015) and heat acclimation (Gibson et al 2015;Mee et al 2015;Willmott et al 2016), that seek to alleviate the significant impairment to endurance performance afforded by heat stress (Guy et al 2015).…”

Pré-condicionamento isquêmico e desempenho: há viabilidade/racionalidade na sua aplicação?

“…O tempo ideal entre o fim da manobra (IPC) e o início do teste ainda não é consenso e varia entre 5 e 90 minutos na maioria dos estudos relacionados ao desempenho 8 . Apesar disso, autores sugerem que o efeito ergogênico agudo ocorreria dentro de 45 minutos a partir do fim da manobra 8,11,12 .…”