1986
DOI: 10.1001/archderm.122.7.779
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Effect of intralesional alpha 2-interferon on actinic keratoses

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Cited by 20 publications
(8 citation statements)
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“…These modified IFNs are expected to have more favourable therapeutic outcomes during treatment of certain conditions such as chronic hepatitis C (CHC) virus infection (5). Recently, IFNs has been also evaluated as a novel therapeutic modalities for other conditions such as systemic sclerosis (6), small cell lung carcinoma (7), malignant mesothelioma (8), malignant pleural effusions (9), pulmonary fibrosis (10,11), multidrug‐resistant tuberculosis (12,13), actinic keratoses (14, 15), atopic dermatitis (16), basal cell carcinomas (17), Behcet's disease (18), mycosis fungoides (19), discoid lupus erythematosus (20), haemangiomas (21) and psoriasis (22).…”
Section: Clinical Use Of Ifns: An Overviewmentioning
confidence: 99%
“…These modified IFNs are expected to have more favourable therapeutic outcomes during treatment of certain conditions such as chronic hepatitis C (CHC) virus infection (5). Recently, IFNs has been also evaluated as a novel therapeutic modalities for other conditions such as systemic sclerosis (6), small cell lung carcinoma (7), malignant mesothelioma (8), malignant pleural effusions (9), pulmonary fibrosis (10,11), multidrug‐resistant tuberculosis (12,13), actinic keratoses (14, 15), atopic dermatitis (16), basal cell carcinomas (17), Behcet's disease (18), mycosis fungoides (19), discoid lupus erythematosus (20), haemangiomas (21) and psoriasis (22).…”
Section: Clinical Use Of Ifns: An Overviewmentioning
confidence: 99%
“…The risk is higher with increase of the number of AK lesions and with time [8,9]. There are many effective treatment modalities for AK: cryosurgery, curettage, electrosurgery, excision, topical 5-fluorouracil (5-FU), chemical peeling, dermabrasion, laser surgery, photodynamic therapy, systemic retinoids, topical tretinoin, intralesional interferon, diclofenac, imiquimod [10,11,12,13,14,15]. For decades 5-FU has been one of the standard treatments for AK [16].…”
Section: Introductionmentioning
confidence: 99%
“…Thus IFNα also exhibits antiproliferative and immunomodulatory functions. [12] Recombinant IFNα is given as a subcutaneous or intramuscular injection to treat verruca vulgaris,[13] condyloma acuminatum,[14] cutaneous T cell lymphoma,[15] Kaposi's sarcoma (AIDS related),[16] melanoma,[17] basal cell carcinoma,[18] squamous cell carcinoma,[19] actinic keratosis,[20] Behçet's disease,[21] hemangiomas[22] and keloids. [23] The injections are usually given thrice weekly and the dose (depending on the condition being treated) varies from low-dose therapy for condyloma acuminatum[24] to high-dose therapy for melanoma.…”
Section: Recombinant Human Cytokines and Growth Factorsmentioning
confidence: 99%