Effect of intra-aortic balloon pumping on nutrient coronary flow in normal and ischemic myocardium

Swank, Michael; Singh, Harjeet; Flemma, Robert J.; Mullen, Donald C.; Lepley, Derward

doi:10.1016/s0022-5223(19)41085-4

Cited by 27 publications

(13 citation statements)

References 8 publications

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“…Reuben et a!. (1975) and Swank et al (1978) injected cold blood into the left atrium and measured the heat change in a local area of the myocardium following injection. The same principle has been applied in the dog kidney in which thermal conductivity was measured after heating a small adjacent area (Muller-Schauenburg et al 1975;Olshausen et al 1976).…”

Section: Discussionmentioning

confidence: 99%

“…under stress). 0144-8757/81/1020-1823 $07.50 ©) 1981 The Physiological Society Local tissue blood supply can be evaluated experimentally as a function of heat transfer or dilution as measured locally by thermistors (Hernandez, Hoffman, Fabian, Siegel & Eherhart, 1979;Muller-Schauenburg, Apfel, Benzing & Betz, 1975;Olshausen, Gross & Kirchein, 1976; Reuben, Singh, Tector, Kampine, Flemma & Lepley, 1975;Shitzer & Eberhart, 1979;Swank, Singh, Flemma, Mullen & Lepley, 1978). In the present communication we describe the application of such a technique for measuring local coronary blood flow using small thermistors.…”

Section: Introductionmentioning

confidence: 99%

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Dynamic Redistribution of Coronary Blood Flow in the Dog as Measured by a Thermistor Technique

1981

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SUMMARYThe effect of heart rate upon the coronary blood supply to the right and left ventricles was studied in anaesthetized, open-chest dogs. Indirect recording of coronary supply was obtained using thermistors placed locally on the surface or in the wall of the ventricles. The validity of the thermistor technique was examined in vivo as well as by using an in vitro laboratory model. Myocardial perfusion was also measured using electromagnetic flowmeters placed around the anterior descending and circumflex arteries, as well as the coronary sinus and Thebesian drainage. It was found that at heart rates lower than about 150/min, coronary perfusion to all areas increased equally as rate was elevated. At higher heart rates, coronary flow to the right ventricle continued to increase linearly with rate, whereas perfusion to the left ventricle either increased much less or declined. It is concluded that tachycardia causes coronary flow to be dynamically redistributed in favour of the right ventricle.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dynamic Redistribution of Coronary Blood Flow in the Dog as Measured by a Thermistor Technique

1981

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“…Since the latter remains constant by autoregulation within perfusion pressures ranging from 45 to 125 mm Hg, it is increased by the IABP in the presence of very low perfusion pressures or when coronary arterial autoregulation is impaired. 14 In animal studies, using animals with normal hearts and intact coronary arteries, the IABP reduced coronary arterial blood flow by decreasing myocardial oxygen demands, 15 whereas in the presence of reperfused myocardium 16 or in CS, 17 it markedly increased the coronary blood flow. Furthermore, IABP has been shown to salvage ischemic and reperfused myocardium.…”

Section: Pathophysiologic Considerationsmentioning

confidence: 99%

Intra‐Aortic Balloon Counterpulsation for the Treatment of Myocardial Infarction Complicated by Acute Severe Heart Failure

Tsagalou

Anastasiou-Nana

Nanas

2009

Congestive Heart Failure

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Intractable heart failure (HF) remains a leading fatal complication of acute myocardial infarction (AMI). Intra-aortic balloon pump (IABP) counterpulsation assists the failing left ventricle and accelerates the functional recovery of stunned myocardium. Despite its remarkable performance, the beneficial effects of the IABP in the setting of acute HF or cardiogenic shock complicating AMI have not been confirmed in a randomized clinical trial. Instead, large amounts of information have been collected in observational studies or in retrospective analyses of randomized trials of reperfusion strategies in patients with AMI. The strategy of "stabilize with IABP, treat with reperfusion, and transfer for complete revascularization" has, thus far, yielded the best outcomes, and every effort should be made to implement this strategy in all patients presenting with AMI and severe HF.

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“…[5][6][7][8] This augmentation of the coronary perfusion pressure enhances coronary blood flow and therefore myocardial oxygen supply. [9][10][11][12][13][14] Furthermore systolic left ventricular oZoading reduces myocardial wall tension and oxygen demand. 6-8 15 16 Although these eVects will reduce the potential for ischaemia to contribute to arrhythmogenesis, it is probable that this mechanism is of minor importance.…”

Section: Discussionmentioning

confidence: 99%

Candida endocarditis of the right heart

Baratella¹,

Dan²,

Fabbri³

1999

Heart

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Objective-To review the eYcacy of intraaortic balloon counterpulsation (IABCP) in medically refractory ventricular arrhythmia. Design-Retrospective analysis of the outcome of patients with ventricular arrhythmia treated with IABCP after transfer between 1992 and 1997. Setting-Tertiary cardiac referral centre. Patients-21 patients (mean age 58 years) who underwent IABCP for control of ventricular arrhythmia. All had significant left ventricular impairment (mean ejection fraction 28.6%); 18 had coronary artery disease. Results-Before IABCP, 10 patients had incessant monomorphic ventricular tachycardia and 11 had paroxysmal ventricular tachycardia and/or ventricular fibrillation (VT/VF). IABCP resulted in suppression of ventricular arrhythmia in 18 patients, of whom 13 were weaned from IABCP. After stabilisation of ventricular arrhythmia, 10 patients were maintained on medical treatment alone and one underwent endocardial resection. IABCP was maintained until cardiac transplantation in five patients. One patient had a fatal arrest before discharge and one died from progressive heart failure. IABCP failed to control ventricular arrhythmia in three patients and was subsequently discontinued. A cardiac assist device was employed in one of these until cardiac transplantation; the other two were eventually stabilised on medical treatment. Nineteen patients were discharged from hospital. Overall survival was 95% at mean follow up of 25.7 months. Conclusions-IABCP can be an eVective means of controlling refractory ventricular arrhythmia, allowing time for the institution of more definitive treatment. (Heart 1999;82:96-100)

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Effect of intra-aortic balloon pumping on nutrient coronary flow in normal and ischemic myocardium

Cited by 27 publications

References 8 publications

Dynamic Redistribution of Coronary Blood Flow in the Dog as Measured by a Thermistor Technique

Dynamic Redistribution of Coronary Blood Flow in the Dog as Measured by a Thermistor Technique

Intra‐Aortic Balloon Counterpulsation for the Treatment of Myocardial Infarction Complicated by Acute Severe Heart Failure

Candida endocarditis of the right heart

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