Effect of gut microbes on olfactory behavior of Drosophila melanogaster larva

Development of Resistance to Clarithromycin and Amoxicillin-Clavulanic Acid in Lactiplantibacillus plantarum In Vitro Is Followed by Genomic Rearrangements and Evolution of Virulence

“…The interactions of L. plantarum and D. melanogaster are currently in the zone of active attention both from the point of view of the fundamental foundations of the host-symbiont interaction and applied aspects related to the emerging possibilities of modulation of neurophysiology and reproduction of the host organism through probiotics ( 48 – 50 ). To date, as a result of studies of the relationship between D. melanogaster and its symbiont L. plantarum , various facets of micro- and macroorganism interaction have been discovered.…”

Insect-Microorganism Interaction Has Implicates on Insect Olfactory Systems

“…Most insects bear microorganisms that influence their health and fitness, and these microorganisms tend to be harbored predominantly in the lumen of the gut [106]. From the current study, it appears that the symbiotic relationship between insects and gut microbiota affects the neural function and behaviors of the hosts as well [107]. The gut microbiota of Drosophila larvae was altered by treatment with antibiotics or probiotics, and the tropism response of the treated larvae to odorants was found to be reduced.…”

“…The gut microbiota of Drosophila larvae was altered by treatment with antibiotics or probiotics, and the tropism response of the treated larvae to odorants was found to be reduced. It was concluded that the microbiota influences homeostatic mechanisms in the host that control Gamma-aminobutyric acid (GABA) production and GABA receptor expression, which are known to affect the olfaction of the host [107,108]. From the available results, it appears that gut bacteria could largely influence insect olfaction by affecting neural circuit communication.…”

Antibiotic-induced socio-sexual behavioral deficits are reversed via cecal microbiota transplantation but not androgen treatment

“…Olfactory behaviors such as sexual odor preference play a critical role in mate choice and reproductive success ( Huo et al, 2018 ), but the impact of gut microbiota on olfactory behaviors has not been previously assessed in mice. However, in Drosophila , ABX treatment has been shown to reduce olfactory responses that were partly restored by probiotic treatment ( Slankster et al, 2019 ). In the present study, male-typical sexual behaviors (e.g., mounting and thrusting) towards an estrus female remained altered by ABX treatment in male mice.…”