Effect of glaucoma implant surgery on intraocular pressure reduction, flare count, anterior chamber depth, and corneal endothelium in primary open-angle glaucoma

Abstract

The advantage of filtering surgery using the EX-PRESS device includes reduced inflammation, and the disadvantages include loss of the CE and reduced effectiveness of NTG.

Changes of corneal endothelial cell density after EX-PRESS® Glaucoma shunt implantation: 2-year follow-up study.

“…However, great attention should be paid in the long-term periods, particularly in case that EX-PRESS ® was applied to younger patients. [13] In Ishida et al's study, there was no significant difference in the ECD between the baseline and 1 year, however there was a significant decrease from the baseline to 2 years [13] in agreement with the results of our study. However, the degree of reduction in the ECD in Ishida et al's [13] study was smaller than ours which may be due to differences in the experimental protocol.…”

Changes of corneal endothelial cell density after EX-PRESS® Glaucoma shunt implantation: 2-year follow-up study.

“…However, great attention should be paid in the long-term periods, particularly in case that EX-PRESS ® was applied to younger patients. [13] In Ishida et al's study, there was no significant difference in the ECD between the baseline and 1 year, however there was a significant decrease from the baseline to 2 years [13] in agreement with the results of our study. However, the degree of reduction in the ECD in Ishida et al's [13] study was smaller than ours which may be due to differences in the experimental protocol.…”

Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study

“…Our results also showed that in shunt-implanted eyes, CECD loss (5.0%) was significant at the last follow-up (>2 years). This was consistent with some Japanese studies showing a 2.5~4% mean CECD decrease 2 years after surgery, [ 30 , 31 ] even though these studies did not compare it with the contralateral eyes. However, other Japanese studies showed that the mean CECD decrease reached 18.0% at 2 years [ 31 ] and 10.3~30.0% at 2~5 years after Ex-PRESS implantation [ 32 ].…”

Ex-Press® Surgery Versus Trabeculectomy for Primary Open Angle Glaucoma with Low Preoperative Intraocular Pressure

“…In the present study, there was no signi cant between-group difference in the reduction ratio of ECD at 2 years post-surgery, but the reduction of ECD was slightly greater in the Trab group. Several studies reported that Trab or EXP reduced the ECD by 2.2-23.0% in a 2-year period [13,17,26,27]; however, in one of the studies the EXP surgery reduced the ECD rapidly [13], whereas others observed that EXP could not reduce ECD rapidly [17,28]. We reported that postoperative ECD varies depending on the insertion position of the EXP [29].…”

Changes of corneal endothelial cell density after EX-PRESS® Glaucoma shunt implantation: 2-year follow-up study.

“…However, great attention should be paid in the long-term periods, particularly in case that EX-PRESS ® was applied to younger patients. [13] In Ishida et al's study, there was no significant difference in the ECD between the baseline and 1 year, however there was a significant decrease from the baseline to 2 years [13] in agreement with the results of our study. However, the degree of reduction in the ECD in Ishida et al's [13] study was smaller than ours which may be due to differences in the experimental protocol.…”

Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study

“…Our results also showed that in shunt-implanted eyes, CECD loss (5.0%) was significant at the last follow-up (>2 years). This was consistent with some Japanese studies showing a 2.5~4% mean CECD decrease 2 years after surgery, [ 30 , 31 ] even though these studies did not compare it with the contralateral eyes. However, other Japanese studies showed that the mean CECD decrease reached 18.0% at 2 years [ 31 ] and 10.3~30.0% at 2~5 years after Ex-PRESS implantation [ 32 ].…”

Ex-Press® Surgery Versus Trabeculectomy for Primary Open Angle Glaucoma with Low Preoperative Intraocular Pressure

“…In the present study, there was no signi cant between-group difference in the reduction ratio of ECD at 2 years post-surgery, but the reduction of ECD was slightly greater in the Trab group. Several studies reported that Trab or EXP reduced the ECD by 2.2-23.0% in a 2-year period [13,17,26,27]; however, in one of the studies the EXP surgery reduced the ECD rapidly [13], whereas others observed that EXP could not reduce ECD rapidly [17,28]. We reported that postoperative ECD varies depending on the insertion position of the EXP [29].…”

Changes of corneal endothelial cell density after EX-PRESS® Glaucoma shunt implantation: 2-year follow-up study.

“…However, great attention should be paid in the long-term periods, particularly in case that EX-PRESS ® was applied to younger patients. [13] In Ishida et al's study, there was no significant difference in the ECD between the baseline and 1 year, however there was a significant decrease from the baseline to 2 years [13] in agreement with the results of our study. However, the degree of reduction in the ECD in Ishida et al's [13] study was smaller than ours which may be due to differences in the experimental protocol.…”

Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study

“…Our results also showed that in shunt-implanted eyes, CECD loss (5.0%) was significant at the last follow-up (>2 years). This was consistent with some Japanese studies showing a 2.5~4% mean CECD decrease 2 years after surgery, [ 30 , 31 ] even though these studies did not compare it with the contralateral eyes. However, other Japanese studies showed that the mean CECD decrease reached 18.0% at 2 years [ 31 ] and 10.3~30.0% at 2~5 years after Ex-PRESS implantation [ 32 ].…”

Ex-Press® Surgery Versus Trabeculectomy for Primary Open Angle Glaucoma with Low Preoperative Intraocular Pressure

“…In the present study, there was no signi cant between-group difference in the reduction ratio of ECD at 2 years post-surgery, but the reduction of ECD was slightly greater in the Trab group. Several studies reported that Trab or EXP reduced the ECD by 2.2-23.0% in a 2-year period [13,17,26,27]; however, in one of the studies the EXP surgery reduced the ECD rapidly [13], whereas others observed that EXP could not reduce ECD rapidly [17,28]. We reported that postoperative ECD varies depending on the insertion position of the EXP [29].…”