Effect of extracts ofOrthosiphon stamineus benth,Hieracium pilosella L.,Sambucus nigra L. andArctostaphylos uva-ursi (L.) spreng. in rats

Abstract

Aqueous extracts of Sambucus nigra and Arctostaphylos uva‐ursi and hydroalcohol extracts of Orthosiphon stamineus and Hieracium pilosella were tested for their diuretic activities in rats; pharmacological evaluation revealed that they led to an increase in urine flow. Urinary sodium excretion in rats was increased with O. stamineus and S. nigra. Copyright © 1999 John Wiley & Sons, Ltd.

Diuretic activity of Sambucus nigraL. ssp. palmensis(Link) R. Bolli, an endemic Canary Islands species

“…The results of this research are in line with those obtained in other studies of other species of Sambucus that indicate diuretic activity (Beaux et al, 1999;Wright et al, 2007). The potential diuretic Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas/ 505 effect of three doses (35.0 mg kg -1 , 52.5 mg kg -1 and 70.0 mg kg -1 ) of Sambucus palmensis (SP) aqueous extract was evaluated in mice and compared to the effect produced by hydrochlorothiazide (HCTZ), a commonly used diuretic drug, and distilled water (control group).…”

Unveiling the Potential Neuroprotective Effect of Bioactive Compounds from Plants with Sedative and Mood-Modulating Properties: Innovative Approaches for the Prevention of Alzheimer's and Parkinson's Diseases

“…Although its leaves and stems are toxic due to their content of cyanogenic glycosides (sambunigrin and prunasin) and m-hydroxysubstituted glycosides (zierin and holocalin), which, after hydrolysis, can release cyanide [ 73 ], the elderflower and fruits are used as herbal medicine and for food purposes [ 74 - 76 ]. Quercetin, rutin, and kaempferol, potent flavonoids, and chlorogenic, caffeic, and protocatechuic acids, known as hydroxycinnamic acids, give elderflower its antibacterial [ 77 ], immunomodulatory [ 78 ], diuretic and anti-diabetic properties [ 79 ]. The antioxidant and protective potential of elderflower were confirmed in the human neuroblastoma SH-SY5Y cell line [ 80 ].…”

Bioactive Compounds as Alternative Approaches for Preventing Urinary Tract Infections in the Era of Antibiotic Resistance

“…Although Arctostaphylos uva-ursi represents a safe therapeutic option for the treatment of lower urinary tract infections, it is important to note that hydroquinone is a potential carcinogen and therefore, it should not be taken chronically [ 83 ]. Of note, Arctostaphylos uva-ursi leaf extracts may cause side effects, including nausea, vomiting, irritability, and insomnia, and it is not recommended for pregnant or lactating women [ 84 , 85 , 86 , 87 ].…”