Abstract:Aging, if accompanied by a sedentary lifestyle, can result in different diseases including cardiovascular diseases. Klotho, a protein found in the kidneys and other tissues of the body, is influenced by age and level of physical activity. In this paper, using 66 papers published in PubMed and SID between 1997 and 2018, we examined the mechanism of action of Klotho on cardiac hypertrophy under senescence conditions. Studies have shown that aging results in the development of oxidative stress as well as increase… Show more
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