Effect of Ethanol Solvent Concentration on Antioxidant Activity of Dolwoe (Gynostemma pentaphyllum Makino) Leaves Extracts

Kim, Kyeoung Cheol; Kim, Ju-Sung

doi:10.35272/jaet.2018.11.3.197

Cited by 3 publications

(1 citation statement)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…RC 50 values of extracts by ethanol extracts of E. japonica leaves are 80% EtOH (61.96 ± 5.01 μg/mL, 60% EtOH (63.87 ± 0.59 μg/mL), 40% EtOH (72.92 ± 05.22 μg/mL), 20% EtOH (75.53 ± 1.14 μg/mL), hot water (102.49 ± 3.04 μg/mL), and 100% EtOH (117.96 ± 0.88 μg/mL), respectively (Figure 2A). This is thought to be a complex action of several compounds extracted according to the intrinsic color and ethanol concentration of E. japonica leaves extract (Kyeoung-Cheol & Ju-Sung, 2018).…”

Section: Dpph Radical Scavengingmentioning

confidence: 99%

Correlation of the free radical and antioxidant activities of Eriobotrya Japonica Lindl. with phenolic and flavonoid contents

2021

View full text Add to dashboard Cite

Section: Dpph Radical Scavengingmentioning

confidence: 99%

Correlation of the free radical and antioxidant activities of Eriobotrya Japonica Lindl. with phenolic and flavonoid contents

2021

View full text Add to dashboard Cite

Effects of Sargassum thunbergii Extract on Skin Whitening and Anti-Wrinkling through Inhibition of TRP-1 and MMPs

et al. 2021

View full text Add to dashboard Cite

Sargassum thunbergii has been traditionally used as an edible and medicinal material in oriental countries. However, the skin-whitening and anti-wrinkling effects of S. thunbergii have not yet been investigated. This study was conducted to establish optimal extraction conditions for the production of bioactive compounds with antioxidant activity as well as skin-whitening and anti-wrinkle effects using ultrasound-assisted extraction (UAE) in S. thunbergii. The extraction time (5.30~18.7 min), extraction temperature (22.4~79.6 °C), and ethanol concentration (0.0~99.5%), which are the main variables of the UAE, were optimized using a central composite design. Quadratic regression equations were derived based on experimental data and showed a high coefficient of determination (R2 > 0.85), demonstrating suitability for prediction. The optimal UAE condition for maximizing all dependent variables, including radical scavenging activity (RSA), tyrosinase inhibitory activity (TIA), and collagenase inhibitory activity (CIA), was identified as an extraction time of 12.0 min, an extraction temperature of 65.2 °C, and ethanol of 53.5%. Under these conditions, the RSA, TIA, and CIA of S. thunbergii extract were 86.5%, 88.3%, and 91.4%, respectively. We also confirmed S. thunbergii extract had inhibitory effects on the mRNA expression of tyrosinase-related protein-1, matrix metalloproteinase-1, and matrix metalloproteinase-9, which are the main genes of melanin synthesis and collagen hydrolysis. Liquid chromatography-tandem mass spectrometry was used to identify the main phenolic compounds in S. thunbergii extract, and caffeic acid was identified as a major peak, demonstrating that high value-added ingredients with skin-whitening and anti-wrinkling effects can be produced from S. thunbergii and used for developing cosmetic materials.

show abstract

Antioxidant and Anti-Inflammatory Effects of Semi-Fermented Tea

Lee

Moon

Chung

et al. 2021

JKFN

View full text Add to dashboard Cite

This study investigated the antioxidant and anti-inflammatory effects of 7 semi-fermented tea from Korea and China. The DPPH and ABTS radical-scavenging activities, and reducing power gradually increased as the concentration increased in all the sample groups. In the DPPH radical-scavenging activity (IC50), domestic oolong tea (Hadong) was 9.99 μg/mL, white tea was 10.44 μg/mL and Junshan Yinzhen tea was 4.99 μg/mL. Junshan Yinzhen tea showed the highest antioxidant effect among other extracts. In the evaluation of ABTS radical-scavenging activities, except Seogwihuang cha (Jeju) and Da Hong Pao tea, other samples showed a higher ABTS radical-scavenging effect compared to the ascorbic acid control group. White tea (Hadong) with a concentration of 100 μg/mL showed a significant nitric oxide (NO) inhibition activity compared to all the other samples by decreasing NO production to 46%. In the analysis of MPTP-induced dopaminergic neurotoxicity in SH-SY5Y cells, domestic white tea (Hadong), Da Hong Pao tea, and Junsan Yinchen tea at a concentration of 100 μg/mL showed results of 68.16%, 69.96%, and 69.14%, respectively. These results indicated 20% higher anti-inflammatory effects compared to the MPTP treatment group. Therefore, our results suggest that domestic semi-fermented tea has good antioxidant and anti-inflammatory effects and is expected to have high utility value as a functional food material.

show abstract

Effect of Ethanol Solvent Concentration on Antioxidant Activity of Dolwoe (Gynostemma pentaphyllum Makino) Leaves Extracts

Cited by 3 publications

References 36 publications

Correlation of the free radical and antioxidant activities of Eriobotrya Japonica Lindl. with phenolic and flavonoid contents

Correlation of the free radical and antioxidant activities of Eriobotrya Japonica Lindl. with phenolic and flavonoid contents

Effects of Sargassum thunbergii Extract on Skin Whitening and Anti-Wrinkling through Inhibition of TRP-1 and MMPs

Antioxidant and Anti-Inflammatory Effects of Semi-Fermented Tea

Contact Info

Product

Resources

About