J. Neurosci. Res. volume 86, issue 13, P3011-3017 2008 DOI: 10.1002/jnr.21736 View full text
Jing Qian, Dong Zhou, Fang Pan, Chun-xi Liu, Yu-wei Wang

Abstract: Prenatal stressed offspring exhibit more fearful behavior in behavioral tests, which can be reversed by environmental enrichment (EE). However, the physiological basis of these phenomena remains unclear. Previous studies revealed that abnormal fearful behavior of prenatally stressed offspring may be a consequence of increased activities of CRFergic systems (corticotropin-releasing factor and its receptors) in the amygdala. Gastrin-releasing peptide receptors (GRPR) also have an important role in regulating amy…

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