Effect of Egg White Gel againts Burn Healing on White Rat (Rattus novergicus)

Hendriati, Lucia; Hamid, Iwan Sahrial; Widodo, Teguh; Wandasari, Chintya; Risata, Putu Mirah

doi:10.35814/jifi.v16i2.532

Cited by 5 publications

(7 citation statements)

References 3 publications

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“…TGF-β secretion starts in the early proliferative phase, then the secretion keeps on going, and reaches its peak on the 7 day. 41,42 That is why the significant differences were found on the 3 days and the 7 days after RH-LS treatment.…”

Section: Discussionmentioning

confidence: 94%

The Role of Rice Hull Liquid Smoke in the Traumatic Ulcer Healing

et al. 2020

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Objective The aim of this study was to prove the role of rice hull liquid smoke (RH-LS) on lymphocytes, macrophages, fibroblasts, interleukin 6 (IL-6), and transforming growth factor β (TGF-β) expression during traumatic ulcer healing. Materials and Methods The RH-LS was obtained from the pyrolysis process. Traumatic ulcers were made 10 mm along the labial fornix incisive inferior of Wistar rat using a round stainless-steel blade. In control group, traumatic ulcers were treated using sterile water, and meanwhile in experimental group were treated using RH-LS once a day for 3, 5, and 7 days. After treatment, animal was terminated and their labial fornix incisive inferior tissues were biopsy and stained using hematoxylin and eosin staining to determine lymphocytes, macrophages, and fibroblasts. The IL-6 and TGF-β expressions were analyzed used immunohistochemistry staining. Result The lymphocytes, macrophages, and fibroblasts were higher in the RH-LS group for 3-, 5-, and 7-day treatment (p < 0.05). The IL-6 expression was higher only in the 5-day treatment, and the TGF-β expression was higher in the 3- and 7-day treatment. Conclusion The RH-LS able to accelerated the traumatic ulcer healing by increasing the number of lymphocytes, macrophages, fibroblasts, IL-6, and TGF-β expression.

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Section: Discussionmentioning

confidence: 94%

The Role of Rice Hull Liquid Smoke in the Traumatic Ulcer Healing

et al. 2020

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“…Researchers can use a measurement of hydroxyproline levels as an index of collagen turnover. Besides this, results use a measurement of the hydroxyproline levels as an index of collagen turnover (28) . The results show a signifi cant diff erence in hydroxyproline levels for the ethanol extract of cinnamon leaves and indicate an increase in breaking down granulation tissue from collagen maturation in injured skin (29,30) .…”

Section: Resultsmentioning

confidence: 99%

In Vivo Incision Wound Healing Studies using Ethanolic Cinnamon’s (Cinnamomum burmannii) Leaves Extract in White Male Rats

Kasmadi

Afrilia

Utami

et al. 2022

jifi

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Cinnamon leaves are traditional plants that contain secondary metabolites such as flavonoids, tannins, saponins, alkaloids, and phenols. All of these compounds play an essential role in the wound healing process. This study aimed to determine the effects of cinnamon (Cinnamomum burmannii) on incision wound healing in male rats. The research method used a post-test only control group design approach that uses five treatment groups: positive control (Bioplacenton® Gel), negative control (Vaseline flavum), and ethanol extract of cinnamon leaves at concentrations of 10%, 20%, and 30%. The results showed that the ethanol extract of cinnamon leaves affected wound healing, as observed from the day of wound healing, the AUC length of the wound, and levels of hydroxyproline. The statistical test results showed a significant difference between the groups (p<0.05), where the best concentration was 30%, followed by 20% and 10%. Therefore, we concluded that the ethanolic extract of cinnamon leaves can heal wounds in male rats.

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“…The mechanism of egg white in wound healing is to form new cell tissue and stimulate the restoration of damaged body tissue. The disadvantage of free-range chicken egg white is that it smells bad so it needs to be processed in gel preparations to increase comfort in use [14]. Egg white contains ovalbumin which has the potential to be used as a drug carrier and as a source of amino acids for growth factors.…”

Section: Egg White Mechanism In Wound Healingmentioning

confidence: 99%

The Fibroblast Cell Numbers After Tooth Extraction by Topical Application of Egg White Gel Toward Iod Glycerin

Saleh¹,

Puspita²,

Utami³

2022

Proceedings of the International Conference on Sustainable Innovation on Health Sciences and Nursing (ICOSI-HSN 2022)

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Background:The results of the Indonesian Basic Health Research in 2018 stated that the index for tooth extraction reached 7.9%, higher than treatments with fillings (4.3%) and scaling (1.4%). Actions resulting from tooth extraction that are slow to heal can cause complaints including pain, swelling, bleeding, and even infection, so proper post-extraction management is needed to reduce the possibility of complications. The drug that is often used for wound healing is glycerin iodine, but iodine itself has irritating and toxic properties if it enters the blood vessels, so glycerin iodine needs to be given another alternative as an antiseptic or healing agent after tooth extraction. Objectives: This review aimed to determine the bioactive substances and the effect of Gallus domesticus egg white gel in increasing the number of fibroblast cells in the wound healing process after tooth extraction through a literature study from researchers which was used as a reference for making this literature review. Method: Data were obtained by data collection methods related to the study being studied and analyzed descriptively. Results: Several literatures conclude about bioactive substances and the effect of Gallus domesticus egg white gel in increasing fibroblast cells. These literatures discuss the effect of using egg white gel in the wound healing process that can stimulate fibroblast cells, antiviral, antibacterial, and growth factors. Implications: This review is expected to provide information in the health sector, especially in the oral cavity about the potential of Gallus domesticus egg white gel as a traditional medicine for wound healing which is relatively inexpensive, easy to obtain and practical.

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Effect of Egg White Gel againts Burn Healing on White Rat (Rattus novergicus)

Cited by 5 publications

References 3 publications

The Role of Rice Hull Liquid Smoke in the Traumatic Ulcer Healing

The Role of Rice Hull Liquid Smoke in the Traumatic Ulcer Healing

In Vivo Incision Wound Healing Studies using Ethanolic Cinnamon’s (Cinnamomum burmannii) Leaves Extract in White Male Rats

The Fibroblast Cell Numbers After Tooth Extraction by Topical Application of Egg White Gel Toward Iod Glycerin

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