Effect of Different Concentration of Intraumblical Injection of Oxytocin and Saline on Third Stage of Labor

Abstract

Objectives: The aim of study is to study the different concentration of intraumblical oxytocin saline injection on duration and blood loss of third stage of labor and other parameter. Methods: After considering inclusion and exclusion criteria, cases were divided in to 5 groups. All Women were injected 50 ml of normal saline into umbilical vein immediately after clamping and cutting the cord, in group A without oxytocin, in Group B with 10 units of oxytocin, in group C with 20 unit oxytocin and in group D with 30 unit oxytocin. In group E (control) women were managed conservatively. Duration and amount of blood loss of third stage was noted. Results: There were total 250 women enrolled in the study. A statistically significant reduction in the duration and amount of blood loss of third stage of labor was found in group B compared to group A. On increasing the concentration of oxytocin from 10 IU to 20 IU a slight reduction in mean duration and amount of blood loss of third stage was noted. On further increasing the concentration of oxytocin to 30 IU a statistical significant reduction was present. Conclusion: For active management of third stage intraumblical injection of oxytocin with saline should be promoted.