Effect of dietary supplementation with olive and sunflower oils on lipid profile and liver histology in rats fed high cholesterol diet

Duavy, Sandra Mara Pimentel; Salazar, Gerson Javier Torres; Leite, Gerlânia de Oliveira; Ecker, Assis; Barbosa, Nilda Vargas

doi:10.1016/j.apjtm.2017.06.001

Cited by 15 publications

(10 citation statements)

References 27 publications

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“…[19]. Sun flower oil decreased LDL-C in our result and it disagreed with previous works [30,31], we believe that the significant reduction of LDL-C may return to delay of absorption of fatty acids from digestive tract. Data presented as mean ± S.E the same letters mean nonsignificant differences while the different letters mean significant differences *= p< 0.05 Data presented as mean ± S.E the same letters mean nonsignificant differences while the different letters mean significant differences *= p< 0.05 Data presented as mean ± S.E the same letters mean nonsignificant differences while the different letters mean significant differences *= p< 0.05…”

Section: Discussioncontrasting

confidence: 99%

Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats

Abdullah¹,

Rasoul²,

Mahmood³

2018

KJAR

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The present study investigates the influence of different dietary plant oils included sunflower oil (SO), olive oil (OO) corn oil (CO), and animal (AF) on different parameters in female albino rats. Twenty-two animals were divided equally and randomly into five groups, the treatment was performed by needle gavage. First group fed on basal diet and served as control. Second group fed on a basal diet with 0.3ml/rat animal fat orally. Third group fed on a basal diet with 0.3ml/rat sunflower oil orally. Fourth group fed on a basal diet with 0.3ml/rat olive oil orally. Fifth group fed on a basal diet with 0.3ml/rat corn oil orally. It continued for 28 days. Several parameters were measured during and after the study such as body weight, food intake, organ weight (kidney, liver and spleen) Haematological parameters (Hb, RBC, WBC, PLT, HCT and MCV), lipid profile (Total cholesterol, TG, HDL and LDL). Commonly plant oils and animal fat showed both benefits and harmful effects on the mentioned parameters; the corn oil and olive oil played important role through generating the healthy signs among other oils and animal fat. The present results concluded that both corn oil and olive oil may own positive effect than the other animal fat sunflower oil of people used in their daily diet.

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Section: Discussioncontrasting

confidence: 99%

Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats

Abdullah¹,

Rasoul²,

Mahmood³

2018

KJAR

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“…The proportion of MUFAs may be a factor that influences the metabolism of cholesterol. showed that the intake of MUFA-rich olive oil reduced serum LDL-C levels compared to a SFO diet [39]. Although similar results were observed in the present study, the mechanisms underlying these results still need to be investigated further.…”

Section: Discussionsupporting

confidence: 85%

“…Besides, LDL-C was highest in mice fed with SFO and SBO. Mara et al compared rats fed with cholesterol + olive oil or cholesterol + soybean oil and results showed that there was no significant difference in the final body weights of the groups, but the LDL-C level of rats fed with cholesterol + soybean oil was over 2 times higher than that of rats fed with cholesterol + olive oil [39]. In the present study, mice fed with SFO and SBO showed lowest HDL-C/LDL-C ratios, suggesting that SFO and SBO diets could lead to cholesterol disorders.…”

Section: Discussionmentioning

confidence: 99%

Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications

et al. 2020

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Background: The traditional Chinese diet blends lard with vegetable oil, keeping the fatty acid balance intake ratio of saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids at nearly 1:1:1. However, the effects of a mixture of lard and vegetable oil on lipid metabolism have never been researched. In the present study, by simulating Chinese high-fat dietary habits, we explored the effects of a mixture of lard and vegetable oil on lipid metabolism. Methods: We randomly assigned 50 male C57BL/6 J mice to 5 groups (10 in each group) and fed them lard, sunflower oil (SFO), soybean oil (SBO), lard blended with sunflower oil (L-SFO), or lard blended with soybean oil (L-SBO) for 12 weeks. Results: We found that the final body weights of mice in the lard group were significantly higher than those of mice in the SFO and SBO groups. Body fat rate and volume of fat cell of the lard group were significantly higher than those of the SFO, SBO, and L-SBO groups. Liver triglyceride level of the lard group increased significantly compared to the other groups. Although body fat rate and liver triglyceride level in the SBO and SFO groups decreased compared to those in the other groups, the high-density lipoprotein cholesterol/low-density lipoprotein cholesterol ratio were also significantly decreased in the SBO and SFO groups. Conclusions: We found that a lard diet induced accumulation of body fat, liver and serum lipids, which can increase the risk of obesity, non-alcoholic fatty acid liver disease, and atherosclerosis. The vegetable oil diet resulted in cholesterol metabolism disorders even though it did not lead to obesity. The mixed oil diet induced body fat accumulation, but did not cause lipid accumulation in the liver and serum. Thus, differential oil/fat diets have an impact on differential aspects in mouse lipid metabolism.

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“…The abundance of unsaturated fatty acids together with antioxidant compounds is an effective choice for lowering the dietary intake of saturated fatty acids and to limit oxidative stress. Oleic acid especially is suggested to reverse induced hyperlipidemia and to have a strong hepatoprotective effect on rats receiving a high fat/high cholesterol diet [83,84]. Depending on the process flow and the final protein content of tiger nut beverages, the determination of protein bioavailability is definitely required to evaluate the effect of lactic fermentation on these nutrients.…”

Section: Products Obtained By Lactic Fermentation or Lactic Acid Bactmentioning

confidence: 99%

Nutritional and Microbiological Quality of Tiger Nut Tubers (Cyperus esculentus), Derived Plant-Based and Lactic Fermented Beverages

et al. 2018

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Tiger nut (Cyperus esculentus) is a tuber that can be consumed raw or processed into beverages. Its nutritional composition shows a high content of lipid and dietary fiber, close to those of nuts, and a high content of starch, like in other tubers. Tiger nuts also contain high levels of phosphorus, calcium, and phenolic compounds, which contribute to their antioxidant activity. From those characteristics, tiger nuts and derived beverages are particularly relevant to limit food insecurity in regions where the plant can grow. In Europe and United States, the tiger nut derived beverages are of high interest as alternatives to milk and for gluten-free diets. Fermentation or addition of probiotic cultures to tiger nut beverages has proven the ability of lactic acid bacteria to acidify the beverages. Preliminary sensory assays concluded that acceptable products are obtained. In the absence of pasteurization, the safety of tiger nut-based beverages is not warranted. In spite of fermentation, some foodborne pathogens or mycotoxigenic fungi have been observed in fermented beverages. Further studies are required to select a tailored bacterial cocktail which would effectively dominate endogenous flora, preserve bioactive compounds and result in a well-accepted beverage.

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Effect of dietary supplementation with olive and sunflower oils on lipid profile and liver histology in rats fed high cholesterol diet

Abstract: HC + OO diet has high absorption velocity in the acinar zone 1 of liver compared to the HC + SO diet. Based on this, the reduction of the LDL-C, VLDL-C and CT serum levels in the animals treated with HC + OO diet may have been caused by the delay in the FA release to the blood.

Cited by 15 publications

References 27 publications

Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats

Effect of Different Dietary Oils and Fat on Body Weight, Food Intake, Some Haematological and Biochemical Parameters in Female Albino Rats

Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications

Nutritional and Microbiological Quality of Tiger Nut Tubers (Cyperus esculentus), Derived Plant-Based and Lactic Fermented Beverages

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