Abstract:Although the effects of nickel chloride (NiCl 2) on the immune system have long been recognized, little is known about the effects of nickel (II) on the cell cycle and related signaling events in immune organs, such as cecal tonsil, a key immune organ of chicken. In the present study, we investigated the effect of NiCl 2 on the cell cycle of cecal tonsil. The cell cycle was detected by the methods of fl ow cytometry (FCM), quantitative real-time PCR (qRT-PCR) and immunohistochemistry (IHC). The results showed … Show more
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