Background
Sodium intake shows a positive correlation with blood pressure, resulting in an increased risk for cardiovascular diseases (CVD). Salt reduction is a key step toward the WHO's goal of 25% reduction in mortality from noncommunicable diseases (NCDs) by 2025. This study aims to assess the current condition and temporal changes of the global CVD burden due to high sodium intake.
Methods
We extracted data from the Global Burden of Disease (GBD) study 2019. The numbers and age-standardized rates of mortality and disability-adjusted life-years (DALYs), stratified by location, sex, and socio-demographic Index (SDI), were used to assess the high sodium intake attributable CVD burden from 1990 to 2019. Stepwise multiple linear regression analysis was performed to evaluate the relationship between the DALYs rates and related factors.
Results
Globally, in 2019, the deaths and DALYs of high sodium-related CVD were 1.72 million and 40.54 million, respectively, increasing by 41.08% and 33.06% from 1990. Meanwhile, the corresponding mortality and DALYs rates dropped by 35.1% and 35.2% respectively. The high-middle and middle SDI quintiles bore almost two-thirds of the CVD burden caused by high sodium, while the high SDI quintile had the lowest DALYs rate with the greatest annual decline. Males and the elderly had a higher risk suffering CVD from high dietary sodium. And the leading causes of high sodium intake attributable CVD burden were ischemic heart disease, stroke, and hypertensive heart disease. Universal health coverage (UHC) was significantly associated with the DALYs rates after adjustment.
Conclusions
From 1990 to 2019, the global CVD burden attributable to high sodium intake has declined with spatiotemporal and sexual heterogeneity. However, it remains a major public health challenge because of the increasing absolute numbers in DALYs and mortality. Improving universal health coverage may serve as an effective strategy to reduce the high sodium-related CVD burden.