2010
DOI: 10.1016/j.nut.2009.08.006
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Effect of Brazil nut supplementation on the blood levels of selenium and glutathione peroxidase in hemodialysis patients

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Cited by 77 publications
(60 citation statements)
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“…Although some in vitro and in vivo studies have clearly shown that selenium plays an important role in brain, Loef et al [43] emphasized that more randomized studies with long-term supplementation are necessary to consolidate the knowledge about the impact of selenium on prevention of dementia. In our study, one Brazil nut daily for 6 months was enough to restore selenium deficiency, confirming other studies [12,44]. Only one nut of this richest food source of selenium contributed with 288.75 µg of selenium daily, increasing selenium intake to more than the recommended levels (55 µg/day), but not exceeding the tolerable upper intake level (400 µg/day) [45].…”
Section: Discussionsupporting
confidence: 90%
“…Although some in vitro and in vivo studies have clearly shown that selenium plays an important role in brain, Loef et al [43] emphasized that more randomized studies with long-term supplementation are necessary to consolidate the knowledge about the impact of selenium on prevention of dementia. In our study, one Brazil nut daily for 6 months was enough to restore selenium deficiency, confirming other studies [12,44]. Only one nut of this richest food source of selenium contributed with 288.75 µg of selenium daily, increasing selenium intake to more than the recommended levels (55 µg/day), but not exceeding the tolerable upper intake level (400 µg/day) [45].…”
Section: Discussionsupporting
confidence: 90%
“…are widely recognized for being high in calories and for their nutritional value (Jayasinghe and Caruso 2011). They have been the focus of numerous studies aiming to extract their main nutritional and functional components (John and Shahidi 2010;Stockler-Pinto et al 2010;Colpo et al 2014).…”
Section: Introductionmentioning
confidence: 99%
“…According to Cominetti et al (2012), a single Brazil nut may have up to 290 μg of Se (about 5-fold the daily dietary requirement). Therefore, this food can be used to increase levels of this mineral in the blood (Stockler-Pinto et al 2010). This information is clinically important because it demonstrates that the inclusion of controlled amounts of Brazil nuts in the diet can be a way to supplement the mineral SELENIUM AND PARKINSON'S DISEASE 1657 in patients with specific needs of Se.…”
Section: Dietary Sources and Nutritional Recommendationsmentioning
confidence: 99%
“…Quantities greater than 400 μg of Se/day (recommendation for adults) are not indicated by threatening intoxication (IOM 2000). Cases of Se poisoning are not common but can cause signs such as hair and body hair alterations, nails and skin abnormalities, garlic breath (Stockler-Pinto et al 2010), lethargy, and amyotrophic lateral sclerosis (Vinceti et al 2014).…”
Section: Dietary Sources and Nutritional Recommendationsmentioning
confidence: 99%