Effect of autoimmune diseases on cognitive function

Lim, Lily Siok Hoon; Lippé, Sarah; Silverman, Earl D.

doi:10.1016/b978-0-444-52910-7.00050-7

Cited by 8 publications

(9 citation statements)

References 83 publications

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“…Thus, based on the present findings, it seems that greater cognitive capacity facilitates adaptation to illness (see also, Lim et al, 2013;Stilley et al, 2010) by permitting those patients, who represent their illness as more controllable, to not engage in such maladaptive coping behaviors. Conversely, according to the findings, at the lower levels of mental flexibility, personal control is related to greater use of wishful thinking, and treatment control is related to more use of palliative coping.…”

Section: Discussionmentioning

confidence: 73%

“…Along the same lines, given that better executive functioning is related to better adaptation to illness (e.g., Lim et al, 2013;Stilley et al, 2010), our second hypothesis was that mental flexibility also facilitates the typically positive association between representations of control and adaptive coping behaviors (Hagger and Orbell, 2003). In other words, we expected the positive relation of perceived control over illness to coping behaviors, such as problem-solving and adherence, as well as its negative relation to avoidance-related coping, to be stronger at higher levels of mental flexibility.…”

Section: The Present Studymentioning

confidence: 94%

“…In turn, cognitive impairment may impact back adaptation to illness and well-being. Several studies have shown that cognitive dysfunction often affects illness prognosis, quality of life, social relationships, and employment status in a array of chronic illnesses (Kessler, Cohen, Lauer, & Kausch, 1992;Lim et al, 2013;Pressler et al, 2010;Stilley, Bender, Dunbar-Jacob, Sereika, & Ryan, 2010;Tchen et al, 2003).…”

Section: Cognitive Functioning and Adaptation To Chronic Illnessmentioning

confidence: 96%

“…Cognitive dysfunction has been reported in patients suffering from systemic diseases, including rheumatoid arthritis (RA; Bartolini et al, 2002;Appenzeller, Bertolo, & Costallat, 2004), systemic lupus erythematosus (SLE; Emori et al, 2005;Watson, Storbeck, Mattis, & Mackay, 2012) and other autoimmune diseases (Lim, Lippe, & Silverman, 2013). The prevalence of cognitive dysfunction in RA is estimated at levels as high as 30% (Appenzeller et al, 2004;Shin, Katz, Wallhagen, & Julian, 2012), while in SLE as high as 60% (Kozora et al, 2015;Sarbu et al, 2015).…”

Section: Cognitive Functioning and Adaptation To Chronic Illnessmentioning

confidence: 98%

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Adaptation to an autoimmune disorder: Does mental flexibility impact illness-related self-regulation?

Karademas

Ktistaki

Dimitraki

et al. 2015

Psychology & Health

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Section: Discussionmentioning

confidence: 73%

Section: The Present Studymentioning

confidence: 94%

Section: Cognitive Functioning and Adaptation To Chronic Illnessmentioning

confidence: 96%

Section: Cognitive Functioning and Adaptation To Chronic Illnessmentioning

confidence: 98%

See 2 more Smart Citations

Adaptation to an autoimmune disorder: Does mental flexibility impact illness-related self-regulation?

Karademas

Ktistaki

Dimitraki

et al. 2015

Psychology & Health

View full text Add to dashboard Cite

show abstract

“…Many medical, neurological and psychiatric illnesses pose their effect on the cognition of an individual. Endocrinopathies, liver disease, chronic renal disease, autoimmune diseases and depression are some of the diseases linked with the decrease in cognition of the individual [6][7][8][9][10] .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Cognitive Decline in Patients With Stroke

Malik

Zubair

Alamgir

et al. 2020

PAFMJ

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Objective: To determine the prevalence of cognitive decline among the patients of stroke and analyze the associated socio demographic factors. Study Design: Cross sectional study. Place and Duration of Study: Tertiary care hospital of Rawalpindi, from May 2018 to Aug 2018. Methodology: The sample population comprised of n=180 patients of hemorrhagic or ischemic stroke presenting at a tertiary care hospital in Rawalpindi, Pakistan. Cognitive decline was assessed by using the British Columbia Cognitive Complaints Inventory (BC-CCI) four weeks after the acute stroke. Relationship of age, gender, marital status, education, type of stroke, presence of physical impairment and tobacco smoking was assessed with the presence of cognitive decline among the patients of stroke. Results: Out of 180 patients of stroke screened through British Columbia Cognitive Complaints Inventory, 129 (71.7%) showed the presence of cognitive decline while 51 (28.3%) had no cognitive decline. After applying the logistic regression we found that female gender and presence of physical impairment had significant association with the presence of cognitive decline among the patients of stroke. Conclusion: This study showed a high prevalence of cognitive decline among the patients of stroke in Pakistan. Routine screening for cognitive decline should be done at the stroke follow up clinic and special attention should be paid to the female patients of stroke and those with physical impairment.

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Interleukin 6 and cognitive dysfunction

Trapero

Cauli

2014

Metab Brain Dis

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The interleukin-6 (IL-6) is a pleiotropic cytokine that plays a key role in interaction between immune and nervous system. Although IL-6 has neurotrophic properties and beneficial effects in the CNS, its overexpression is generally detrimental, adding to the pathophysiology associated with CNS disorders. The source of the increase in peripheral IL-6 remains to be established and varies among different pathologies, but has been found to be associated with cognitive dysfunction in several pathologies. This comprehensive review provides an update summary of the studies performed in humans concerning the role of central and peripheral IL-6 in cognitive dysfunction in dementias and in other systemic diseases accompained by cognitive dysfuction such as cardiovascular, liver disease, Behçet's disease and systemic lupus erythematosus. Further research is needed to correlate specific deficits in IL-6 and its receptors in pathologies characterized by cognitive dysfunction and to understand how systemic IL-6 affects high cerebral function in order to open new directions in pharmacological treatments that modulate IL-6 signalling.

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Effect of autoimmune diseases on cognitive function

Cited by 8 publications

References 83 publications

Adaptation to an autoimmune disorder: Does mental flexibility impact illness-related self-regulation?

Adaptation to an autoimmune disorder: Does mental flexibility impact illness-related self-regulation?

Prevalence of Cognitive Decline in Patients With Stroke

Interleukin 6 and cognitive dysfunction

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