Effect of associated vaccines on the interference between Newcastle disease virus and infectious bronchitis virus in broilers

Abstract

The phenomenon of viral interference between live vaccines against Newcastle Disease and infectious bronchitis has been reported since the 50's and many researchers have reported its prejudicial effects on avian immunization. Therefore, this study evaluated the effect of associated vaccines on the interference between Newcastle disease virus (NDV) and infectious bronchitis virus (IBV) in broilers. There were 400 broiler chicks divided into five groups. The groups were submitted to mono or polyvalent vaccinations against IBV and NDV, except for the non-vaccinated control group (CG). Sera were collected at 35 and 45 days of age and submitted to serologic tests to assess antibody levels. It was observed the occurrence of interference in the immune response against NDV by the use of associated vaccines to NDV and IBV; however, the group that was immunized with commercial combined vaccines (IBV+NDV) presented antibody titers to NDV similar to the group that was given only vaccine against NDV. We concluded based on these preliminary studies that the interference of IBV on the immune response against NDV depends also whether the association between the two vaccines is done just before vaccination or in the manufacturing laboratory

Evaluation of Newcastle Disease antibody titers in backyard poultry in Germany with a vaccination interval of twelve weeks

“…In literature, it has already been shown that a one-time vaccination with the IB/ND vaccine used in this study can induce a moderate antibody titer which can be verified 40 days post vaccination [32]. It is very likely that the same effect appears if the monovalent ND vaccine is used [33]. The statistical data evaluation showed that the titer of the ND vaccination increased significantly with a doubling of vaccinations.…”

“…Negative effects on antibody production after a vaccination with mixed monovalent-vaccines against NDV and IBV are well known [42], since the IB-Virus vaccination seems to decrease the capacity of the gland of Harder [43]. This effect does not seem to occur when the combination of both viruses had been carried out by the manufacturer as in case of the IB/ND vaccine used in this study [33]. Interestingly, a study on vaccination against NDV with different vaccines showed that the combined IB/ND vaccine used in this study induces higher antibody production than other combined IB/ND vaccines or an ND vaccine alone after single vaccination.…”

Respons Imun Ayam Petelur Pascavaksinasi Newcastle Disease dan Egg Drop Syndrome

“…Virus EDS dapat ditularkan melalui udara tercemar, tumbuh di epitel permukaan rongga hidung kemudian diikuti dengan viremia dan antigen dapat terdeteksi di jaringan limfoid (Hafez, 2011 (Hewajuli and Dharmayanti, 2015;Kencana et al, 2015). Penggunaan vaksin aktif maupun inaktif tunggal maupun kombinasi telah diterapkan secara luas pada peternakan unggas (Kencana, et al, 2015;Kencana et al, 2016;Wibowo et al, 2010 (Cardoso et al, 2005). Hasil penelitian dengan vaksin kobinasi Sanavac ND-AI ternyata mampu merangsang titer antibodi protektif baik pada ayam SPF maupun pada aplikasi lapangan (Kencana et al, 2015;Kencana et al, 2016).…”

Seroprevalensi Penyakit Egg Drop Syndrome pada Itik di Desa Tumbak Bayuh, Kecamatan Mengwi, Badung, Bali

“…Keuntungannya karena vaksin kombinasi dapat diberikan sekaligus untuk mencegah lebih dari satu penyakit tergantung kombinasinya sehingga memiliki risiko stres yang minimal pada ayam akibat vaksinasi yang berulang . Penggunaan vaksin kombinasi kadangkala juga dapat mempengaruhi efektivitas vaksin dalam menginduksi pembentukan antibodi yang protektif (Cardoso et al, 2005). Pengambilan sampel darah dilakukan satu kali.…”