This investigation is concentrated on how hematological markers would change in pig fat induced metabolism syndrome (MS) in adult Wistar rats. The objective of the current work was to examine the effect of diet-induced metabolic syndrome on hematological parameters. Metabolic syndrome was induced by feeding rats with diet supplemented to 10% (LF group) and 30% (HF group) pig fat and the control rats were fed normal diet (ND) for 9 weeks. After the study period, White Blood Cell (WBC), Red Blood Cell (RBC), hematocrit (HCT), Hemoglobin, platelet (PLT), lymphocytes, monocytes, Neutrophils, Mean Corpuscular Hemoglobin Concentration (MCHC), Mean Corpuscular Volume (MCV) were measured using BC-30s hematology analyzer. The results showed that hematocrit, RBC and hemoglobin levels were significantly decreased in metabolic syndrome than in control rats respectively (37.24±10.3 vs 33.16±9.5%; 7.08±3.2 vs 6.63±2.8x10 6 /μL and 13.36±1.3 vs 11.85±1.2g/L; p< 0.05). MCHC and platelet were also not elevated in metabolic syndrome than in control rats respectively (31.5±8.2 vs 45.3±10.4 and 356.6±92.2g/dl vs 485.2±89.4x10 6 μL; p<0.05). However, erythrocyte indices as MCV didn't showed statistically significant variations among the LF and control rats (56.08±2.01 vs 55.4±2.8fl; p<0.05). MS appeared to significantly decrease to white blood cell concentration, lymphocytes and neutrophils which probably reduced the immune defense mechanism. The findings demonstrated that MS caused significant undesirable alterations in hematological parameters in rats and it possible to suspect a coexistence between anemia and the metabolic syndrome in this animal model. In conclusion, the rats induced fat metabolism syndrome affected hematocrit and hemoglobin levels and it possible to suspect a coexistence between metabolic syndrome and the anemia in this animal model.