Effect of acetylsalicylic acid on the current–voltage characteristics of planar lipid membranes

Abstract

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Pore Formation in Lipid Bilayer Membranes made of Phosphatidylcholine and Cholesterol Followed by Means of Constant Current

“…The effect of cholesterol on phosphatidylcholine membrane capacitance and resistance has been extensively studied [41, 42]. Our present results confirm the earlier observations in demonstrating that cholesterol induces changes in the PC bilayer including reduced mobility of the alkyl chains, greater membrane order and stiffness, and lower permeability.…”

Chronopotentiometric Investigation of the Influence of Cholesterol and Ionic Strength on Lipid Bilayer's Physicochemical Properties

“…Incorporation of cholesterol in both model and biological membranes induces diverse changes in the bilayer properties. For example, this reduces molecular surface area 26 and membrane permeabilities, 39 alters lateral diffusion rates for both proteins and lipids, 40,41 broadens gel to liquid-crystalline phase transition and moderates acyl chain order in both the gel and liquid-crystalline phases. 42 The resistance values for the different compositions of both the membrane and the solution were obtained in separate experiments, hence the uniqueness and great scatter of the results.…”

Cyclic Voltammetry and Chronoamperometry Techniques in Description of the Surface-Active Phospholipid Bilayer Relative to Acid-Base Equilibria

“…A number of electroanalytical techniques have been utilized for placing the electrodes on both sides of the membrane, through which a host of properties associated with the lipid bilayer can be readily investigated. [11][12][13] By studying such a planar lipid bilayer over the past decades, much insight has been obtained including light conversion, ligand-receptor interactions, ion transport, signal transduction and information processing, to name a few. [14][15][16][17][18] Although the planar BLM has proved to be an ideal system for basic research, it has one major deficiency, namely fragility.…”