1957
DOI: 10.3181/00379727-94-23013 View full text |Buy / Rent full text
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Abstract: It has been shown that lesions in the anterior hypothalamus will interfere with secretion of thyrotropin by the pituitary ( 1-4).Since it has not yet been ascertained whether the hypothalamus exerts a primary role in controlling thyrotropin secretion or merely transmits influences from higher centers, the present investigation was undertaken. Originally, it was planned to study thalamic preparations, but it was not possible to keep such animals alive more than one week in spite of forced-feeding and daily anti… Show more

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“…DISCUSSION Previous studies have shown that only lesions in the so called "thyrotropin area" of the hypothalamus, in the midline between the paraventricular nucleus and the median eminence, consistently result in diminution of thyrotropin secretion by the pituitary (7). It has also been shown that the neocortex is not essential to thyrotropin release in the rat (8). Such studies suggest that the hypothalamus may be a primary center controlling thyrotropin secretion from the pituitary although the possibility remains that the hypothalamus is merely an intermediate area transmitting impulses from higher centers to the pituitary.…”
Section: Histological Examinationsmentioning
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“…DISCUSSION Previous studies have shown that only lesions in the so called "thyrotropin area" of the hypothalamus, in the midline between the paraventricular nucleus and the median eminence, consistently result in diminution of thyrotropin secretion by the pituitary (7). It has also been shown that the neocortex is not essential to thyrotropin release in the rat (8). Such studies suggest that the hypothalamus may be a primary center controlling thyrotropin secretion from the pituitary although the possibility remains that the hypothalamus is merely an intermediate area transmitting impulses from higher centers to the pituitary.…”
Section: Histological Examinationsmentioning