Effect of a Web-Based Management Guide on Risk Factors in Patients With Type 2 Diabetes and Diabetic Kidney Disease

Chan, Juliana C.N.; Thewjitcharoen, Yotsapon; Nguyen, Thy Khue; Tan, Alexander; Chia, Yook Chin; Hwu, Chii‐Min; Du, Juan; Himathongkam, Thep; Wong, K V; Choi, Yun-Mi; Mirasol, Roberto; Mohamed, Mafauzy; Kong, Alice P.S.; Ronald, C.; Chow, Elaine; Ozaki, Risa; Lau, Vanessa; Fu, Amy W. C.; Hong, Eun‐Gyoung; Yoon, Kun‐Ho; Tsang, Chiu-Chi; Lau, Eric S.H.; Lim, Lee‐Ling; Luk, Andrea

doi:10.1001/jamanetworkopen.2022.3862

Cited by 21 publications

(24 citation statements)

References 42 publications

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“…Як і в настанові 2020 року, у настанові 2022 року підтримується комплексний підхід до оцінювання численних чинників ризику цих несприятливих наслідків і партнерська співпраця з пацієнтами та системами охорони здоров'я для впровадження методів лікування, що ґрунтуються на доказах. Доведено, що завдяки такому багатофакторному підходу до лікування під час РКД можна отримати кращі результати [3][4][5][6].…”

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Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence

Rossing¹,

Caramori²,

Chan

et al. 2023

KIDNEYS

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Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence

Rossing¹,

Caramori²,

Chan

et al. 2023

KIDNEYS

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“…The negative associations between healthy lifestyle and age at diagnosis might be confounded by behavioral changes after diagnosis although results were consistent in newly diagnosed patients. The JADE Register uses a pragmatic design to implement data-driven integrated care in a real-world setting [ 38 , 39 ]. Thus, instead of using complex instruments, we used simple questionnaires based on available evidence to assess behavioral factors.…”

Section: Discussionmentioning

confidence: 99%

Combined associations of family history and self-management with age at diagnosis and cardiometabolic risk in 86,931 patients with type 2 diabetes: Joint Asia Diabetes Evaluation (JADE) Register from 11 countries

Cheung

Lau

Tsui

et al. 2022

BMC Med

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Background Family history (FamH) of type 2 diabetes might indicate shared genotypes, environments, and/or behaviors. We hypothesize that FamH interacts with unhealthy behaviors to increase the risk of early onset of diabetes and poor cardiometabolic control. Methods In a cross-sectional analysis of the prospective Joint Asia Diabetes Evaluation Register including patients from 427 clinics in 11 Asian countries/regions in 2007–2021, we defined positive FamH as affected parents/siblings and self-management as (1) healthy lifestyles (balanced diet, non-use of alcohol and tobacco, regular physical activity) and (2) regular self-monitoring of blood glucose (SMBG). Results Among 86,931 patients with type 2 diabetes (mean±SD age: 56.6±11.6 years; age at diagnosis of diabetes: 49.8±10.5 years), the prevalence of FamH ranged from 39.1% to 85.3% in different areas with FamH affecting mother being most common (32.5%). The FamH group (n=51,705; 59.5%) was diagnosed 4.6 years earlier than the non-FamH group [mean (95% CI): 47.9 (47.8–48.0) vs. 52.5 (52.4–52.6), logrank p<0.001]. In the FamH group, patients with both parents affected had the earliest age at diagnosis [44.6 (44.5–44.8)], followed by affected single parent [47.7 (47.6–47.8)] and affected siblings only [51.5 (51.3–51.7), logrank p<0.001]. The FamH plus ≥2 healthy lifestyle group had similar age at diagnosis [48.2 (48.1–48.3)] as the non-FamH plus <2 healthy lifestyle group [50.1 (49.8–50.5)]. The FamH group with affected parents had higher odds of hyperglycemia, hypertension, and dyslipidemia than the FamH group with affected siblings, with the lowest odds in the non-FamH group. Self-management (healthy lifestyles plus SMBG) was associated with higher odds of attaining HbA1c<7%, blood pressure<130/80mmHg, and LDL-C<2.6 mmol/L especially in the FamH group (FamH×self-management, pinteraction=0.050–0.001). Conclusions In Asia, FamH was common and associated with young age of diagnosis which might be delayed by healthy lifestyle while self management was associated with better control of cardiometabolic risk factors especially in those with FamH.

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“…Control of multiple cardiometabolic risk factors and use of organ protective drugs have been shown to reduce the development and progression of cardiovascular-renal complications in patients with T2D [12,25,26], including a recent multi-centre trial incorporating JADE Program among patients with DKD [27]. Since 1995, our hospital had implemented a series of quality improvement program focusing on structured assessment and empowerment which became a territorywide program [11].…”

Section: Discussionmentioning

confidence: 99%

A randomized clinical trial of genetic testing and personalized risk counselling in patients with type 2 diabetes receiving integrated care -The genetic testing and patient empowerment (GEM) trial

Ching-Wan

Xie

Poo

et al. 2022

Diabetes Research and Clinical Practice

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Effect of a Web-Based Management Guide on Risk Factors in Patients With Type 2 Diabetes and Diabetic Kidney Disease

Abstract: This randomized clinical trial examines the use of a web portal combined with a physician-and-nurse care team approach in improving patient involvement and treatment outcomes for type 2 diabetes and diabetic kidney disease.

Cited by 21 publications

References 42 publications

Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence

Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence

Combined associations of family history and self-management with age at diagnosis and cardiometabolic risk in 86,931 patients with type 2 diabetes: Joint Asia Diabetes Evaluation (JADE) Register from 11 countries

A randomized clinical trial of genetic testing and personalized risk counselling in patients with type 2 diabetes receiving integrated care -The genetic testing and patient empowerment (GEM) trial

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