Effect of a propolis extract on Streptococcus mutans counts in vivo

Abstract

Objective: To evaluate the antibacterial action of an extract of geopropolis produced by the bee Melipona compressipes fasciculata on the concentration of Streptococcus mutans colonizing the oral cavity of young patients. Forty-one young volunteers performed 21 mouth rinses divided into three rinses per day for 7 days, with no other changes in their oral hygiene and dietary habits. Saliva was collected at three time points: before the first rinse, and one hour and 7 days after the first rinse. A reduction in the concentration of S. mutans was observed in 49% of all samples collected after use of the extract, 26% showed no alterations, and an increasing in S. mutans was observed in 25%. Was performed with the Statistica for Windows 5.9 program using the Kruskal-Wallis test for analysis of variance and the Mann-Whitney U test, with the level of significance set at 5%. The propolis extract possesses in vivo antimicrobial activity against S. mutans present in the oral cavity and might be used as an alternative measure to prevent dental caries.

Action Of Propolis On Microorganisms Of The Oral Cavity: An Integrative Review

“…All publications were made in Brazil, highlighting the South Region, with 4 articles [9,10,[16][17]; Northeast Region, with 4 articles [11][12][13]15]; and only 1 in the Midwest Region [14].…”

“…Journals that published the articles were: Brazilian Dental Science [9], Journal of Applied Oral Science [10,13], Pesq Bras Odontopediatria Clinica Integrada [11,15], Revista Brasileira de Farmacognosia [12], Rev. Ciência Farmacêutica Básica Aplicada [14], Brazilian Journal of Microbiology [16], Revista de Microbiologia [17].…”

“…The method of six articles [10-12, 14, 16-17] The in vitro study was considered weak evidence, one of them being combined with the experimentally [17]; and three clinical trials [9,13,15], with evidence level 3, as were a few patients.…”

“…After reviewing the research, the action of propolis on the microorganisms of the oral cavity referred to by the authors was: antibacterial action, with reports in 8 articles [9][10][11][12][13][14][15][16]; and antifungal action in three articles [10,[16][17].…”

Ação terapêutica da própolis em lesões cutâneas

“…Martinez Garcia et al (14) ;Duailibe et al (15) Clinical -Antimicrobial action Azevedo et al (4) ;Santos et al (11) ; Lofuto et al (35) Clinical -Therapeutic action in wound healing Peruchi et al (2) ;Park et al (3) ;Vargas et al (5) ; Fernandes Júnior et al (6) ; Silva et al (7) ;Sforcin et al (8) ; Sforcin et al (9) ;Oliveira et al (10) ; Auricchio et al (35) ; Fernandes Júnior et al (17) ;Machado et al (18) ;Longhini et al (19) ;Sawaya et al (20) ;Fernandes et al (21) ;Fernandes Júnior et al ( 22) ; Muli et al (23) ;Gebara et al (24) ;Fernandes Júnior et al (25) ;Bianchini et al (26) ;Gonçales et al (27) ;Dantas et al (28) ; Ayres et al (29) ;Orsi et al (30) ;Orsi et al (31) ;Sforcin et al (32) ;Sforcin et al (33) ;Orsi et al (34) ; Fernandes Júnior et al (36) ;Fernandes et al (37) ; Araújo et al (38) Experimental -Antimicrobial action Rahal et al (16) Experimental -Therapeutic action in wound healing (1) . Another study, which used propolis ointment on 22 chronic wounds, of which 11 were venous ulcers, seven pressure ulcers, two diabetic ulcers, and two post-trauma injuries, found that necrotic tissue was present in 14 (8.2%) during tissue assessment process.…”