Effect of a Multipurpose Contact Lens Solution on the Survival and Binding of Acanthamoeba Species on Contact Lenses Examined With a No-Rub Regimen

Abstract

The efficacy of RMP for Acanthamoeba was not appreciably altered in the presence of organic soil in a no-rub protocol. The antimicrobial activity, in part, appeared to be a combination of reducing the capacity for binding of representative Acanthamoeba to the lens by alteration of morphology, often followed by lysis of the amoebae.

Differential Antimicrobial Efficacy of Multipurpose Solutions against Acanthamoeba Trophozoites

“…The field of Acanthamoeba keratitis research and contact lens disinfection agents sometimes contains contentious or differing results, often attributable to varying methods of investigation and quantification. Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products 29 . Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist.…”

“…Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products. 29 Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist. For instance, the OPTI-FREE products have been previously demonstrated as highly effective against Acanthamoeba trophozoites.…”

Differential Antimicrobial Efficacy of Multipurpose Solutions against Acanthamoeba Trophozoites

“…The field of Acanthamoeba keratitis research and contact lens disinfection agents sometimes contains contentious or differing results, often attributable to varying methods of investigation and quantification. Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products 29 . Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist.…”

“…Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products. 29 Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist. For instance, the OPTI-FREE products have been previously demonstrated as highly effective against Acanthamoeba trophozoites.…”

Knowledge, Behavior, and Free-Living Amoebae Contamination of Cosmetic Contact Lens Among University Wearers in Thailand: A Cross-Sectional Study

“…A previous study of six multipurpose contact lens solutions found that after 24 hr of exposure, all solutions killed at least 99.9% of the trophozoites and cysts. 38,50 However, some multipurpose solutions that are ineffective against Acanthamoeba of multiple genotypes have been reported. 51,52 It has been reported that Vahlkampfia and Hartmannella can also be associated with keratitis.…”

Anti‐ Acanthamoeba Activities of Silica Nanoformulated Quercetin Compound Derived From Annona muricata L. Leaves

“…MPSs have been found ineffective in eliminating Acanthamoeba trophozoites, cysts, bacteria, and fungi. Therefore, incorporating broad‐spectrum antimicrobial agents into MPS is essential [ 65 ].…”

Differential Antimicrobial Efficacy of Multipurpose Solutions against Acanthamoeba Trophozoites

“…The field of Acanthamoeba keratitis research and contact lens disinfection agents sometimes contains contentious or differing results, often attributable to varying methods of investigation and quantification. Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products 29 . Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist.…”

“…Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products. 29 Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist. For instance, the OPTI-FREE products have been previously demonstrated as highly effective against Acanthamoeba trophozoites.…”

Knowledge, Behavior, and Free-Living Amoebae Contamination of Cosmetic Contact Lens Among University Wearers in Thailand: A Cross-Sectional Study

“…A previous study of six multipurpose contact lens solutions found that after 24 hr of exposure, all solutions killed at least 99.9% of the trophozoites and cysts. 38,50 However, some multipurpose solutions that are ineffective against Acanthamoeba of multiple genotypes have been reported. 51,52 It has been reported that Vahlkampfia and Hartmannella can also be associated with keratitis.…”

Anti‐ Acanthamoeba Activities of Silica Nanoformulated Quercetin Compound Derived From Annona muricata L. Leaves

“…MPSs have been found ineffective in eliminating Acanthamoeba trophozoites, cysts, bacteria, and fungi. Therefore, incorporating broad‐spectrum antimicrobial agents into MPS is essential [ 65 ].…”

Differential Antimicrobial Efficacy of Multipurpose Solutions against Acanthamoeba Trophozoites

“…The field of Acanthamoeba keratitis research and contact lens disinfection agents sometimes contains contentious or differing results, often attributable to varying methods of investigation and quantification. Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products 29 . Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist.…”

“…Fortunately, the methods used in this investigation demonstrated similar results to what has been reported for other global products. 29 Furthermore, despite a field of varied reports, some consistencies in the use of certain biocides against Acanthamoeba persist. For instance, the OPTI-FREE products have been previously demonstrated as highly effective against Acanthamoeba trophozoites.…”

Knowledge, Behavior, and Free-Living Amoebae Contamination of Cosmetic Contact Lens Among University Wearers in Thailand: A Cross-Sectional Study

“…A previous study of six multipurpose contact lens solutions found that after 24 hr of exposure, all solutions killed at least 99.9% of the trophozoites and cysts. 38,50 However, some multipurpose solutions that are ineffective against Acanthamoeba of multiple genotypes have been reported. 51,52 It has been reported that Vahlkampfia and Hartmannella can also be associated with keratitis.…”

Anti‐ Acanthamoeba Activities of Silica Nanoformulated Quercetin Compound Derived From Annona muricata L. Leaves

“…MPSs have been found ineffective in eliminating Acanthamoeba trophozoites, cysts, bacteria, and fungi. Therefore, incorporating broad‐spectrum antimicrobial agents into MPS is essential [ 65 ].…”