Climate change has many negative effects on the viticulture sector, as it does in all sectors. In recent years, global climate change has also shown its effect in the form of sudden climatic events. There is an urgent need to develop preventive/protective activities for all plant species in order to prevent the increasing world population from being negatively affected by many negative consequences of climate change such as increasing temperatures, drought, floods, and sudden climatic events. Grape industry is among the sectors that feel the negative effects of climate change the most, and this effect is increasing every year. Along with global warming, there are also important problems in accessing water. Particularly, there is a need to develop cultivars that are more resistant to drought stress and to make applications that will protect grapevine plants from drought stress. One of the most important issues to be overcome is to develop new cultivars that can withstand different stress conditions and to use them more in production. In addition, environmental and human health awareness is increasing day by day. Adaptation strategies to be taken against the negative effects of climate change and the studies to be carried out, as well as the use of new environmentally friendly varieties (requiring less input costs) to be developed in accordance with the sustainable agriculture model, will make significant contributions to protecting both the environment and human health.