Editorial: Seizures with meningioma

Mj, Shepard; Wj, Elias

doi:10.3171/2015.5.jns15935

Cited by 5 publications

(4 citation statements)

References 12 publications

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“…3,6,23 Several nonrandomized studies have demonstrated a benefit to this practice, resulting in early postoperative seizure rates as low as 1.4% to 2.5%. 11,12,18,25 On the other hand, numerous prospective clinical trials 5,6,9,24 and meta-analyses 13,14 have shown no detectable seizure reduction upon the administration of various antiepileptic agents. To date, no study has examined this topic by comparing the most commonly prescribed AED (levetiracetam) to a placebo.…”

Section: Discussionmentioning

confidence: 99%

Prophylactic antiepileptic drug administration following brain tumor resection: results of a recent AANS/CNS Section on Tumors survey

Dewan

Thompson

Kalkanis

et al. 2016

JNS

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OBJECTIVE Antiepileptic drugs (AEDs) are often administered prophylactically following brain tumor resection. With conflicting evidence and unestablished guidelines, however, the nature of this practice among tumor surgeons is unknown. METHODS On November 24, 2015, a REDCap (Research Electronic Database Capture) survey was sent to members of the AANS/CNS Section on Tumors to query practice patterns. RESULTS Responses were received from 144 individuals, including 18.8% of board-certified neurosurgeons surveyed (across 86 institutions, 16 countries, and 5 continents). The majority reported practicing in an academic setting (85%) as a tumor specialist (71%). Sixty-three percent reported always or almost always prescribing AED prophylaxis postoperatively in patients with a supratentorial brain tumor without a prior seizure history. Meanwhile, 9% prescribed occasionally and 28% rarely prescribed AED prophylaxis. The most common agent was levetiracetam (85%). The duration of seizure prophylaxis varied widely: 25% of surgeons administered prophylaxis for 7 days, 16% for 2 weeks, 21% for 2 to 6 weeks, and 13% for longer than 6 weeks. Most surgeons (61%) believed that tumor pathology influences epileptogenicity, with high-grade glioma (39%), low-grade glioma (31%), and metastases (24%) carrying the greatest seizure risk. While the majority used prophylaxis, 62% did not believe or were unsure if prophylactic AEDs reduced seizures postoperatively. The vast majority (82%) stated that a well-designed randomized trial would help guide their future clinical decision making. CONCLUSIONS Wide knowledge and practice gaps exist regarding the frequency, duration, and setting of AED prophylaxis for seizure-naive patients undergoing brain tumor resection. Acceptance of universal practice guidelines on this topic is unlikely until higher-level evidence supporting or refuting the value of modern seizure prophylaxis is demonstrated.

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Section: Discussionmentioning

confidence: 99%

Prophylactic antiepileptic drug administration following brain tumor resection: results of a recent AANS/CNS Section on Tumors survey

Dewan

Thompson

Kalkanis

et al. 2016

JNS

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“…As slow growing extra‐axial tumors, they are more often associated with epilepsy than rapidly growing extra‐axial tumors. The growth rate could allow for the changes required for epileptogenesis, although the precise nature of this process is unclear 1 . Seizures are one of the most common manifestations of supratentorial meningiomas, often as an initial symptom in approximately 25% of patients 2 .…”

Section: Introductionmentioning

confidence: 99%

Factors associated with preoperative and early and late postoperative seizures in patients with supratentorial meningiomas

Bogdanović

Ristić

Baščarević

et al. 2023

Epileptic Disorders

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Objective: Risk factors for epilepsy in meningioma patients are not yet clearly defined, however, seizure freedom is a significant factor for quality of life after surgery. Methods:We performed a retrospective study of the 333 adult patients who received surgery for supratentorial meningioma at our center. Various clinical, radiological, and surgical variables were included in the multivariate regression, and the outcomes measured were the occurrence of seizure(s) preoperatively, during the hospitalization, and during the follow-up period.Results: A total of 89 (26.7%) patients experienced preoperative seizures, of whom 62.9% were seizure free after the surgery. Of 244 patients without epilepsy before surgery, 11.9% had at least one seizure postoperatively. In total, 63 of our patients (18.9%) experienced seizures after the surgery, of whom 20 had refractory epilepsy.Multivariate analysis identified the following predictors of preoperative seizures: the

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“…Even though meningioma has a high survival rate (81.5% survival rate in 10 years), patients may develop sequalae either due to its mass effect or as a manifestation of post-operative surgical complications [2]. In a study by Liouta et al, intracranial meningioma may also exert neurocognitive deterioration in which many of their subjects developed a reduction in scores in cognitive function such as memory, attention, visuospatial function and fine motor performance [3]. However, the most debilitating sequelae that can occur is when the visual function is impaired.…”

Section: Discussionmentioning

confidence: 99%

“…The most common location for meningioma to arise is within the cerebellar meninges that accounts for almost 90% of the cases [2]. Patients with meningioma usually demonstrate symptoms of generalized headache, dizziness, seizure, deterioration of cognitive and motor function, and visual disturbances [3].…”

Section: Introductionmentioning

confidence: 99%

Bilateral Inferior Altitudinal Visual Field Defect in Recurrent Intracranial Meningioma: A Case Report

Zamli¹,

Chew-Ean²,

Hitam³

2019

Cureus

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Altitudinal visual field defect is a rare presentation of retrochiasmal lesion especially when bilateral visual fields were affected. In fact, bilateral inferior altitudinal visual field defect (BIAVFD) usually occurred in patients who survived a gunshot injury to the occipital lobe or as a direct trauma to the brain. We report a rare case of BIAVFD secondary to occipital meningioma. A high index of suspicion enables timely investigation and diagnosis when dealing with atypical presentation of intracranial meningioma.

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Editorial: Seizures with meningioma

Cited by 5 publications

References 12 publications

Prophylactic antiepileptic drug administration following brain tumor resection: results of a recent AANS/CNS Section on Tumors survey

Prophylactic antiepileptic drug administration following brain tumor resection: results of a recent AANS/CNS Section on Tumors survey

Factors associated with preoperative and early and late postoperative seizures in patients with supratentorial meningiomas

Bilateral Inferior Altitudinal Visual Field Defect in Recurrent Intracranial Meningioma: A Case Report

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