Economic Evaluation of HLA-B*15:02 Genotyping for Asian Australian Patients With Epilepsy
Yaron Gu,
Sophy T. F. Shih,
Nimeshan Geevasinga
et al.
Abstract:ImportanceThe HLA-B*15:02 allele has been associated with an increased risk of carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in specific Asian populations (including Han Chinese, Malaysian, Thai, and Vietnamese individuals). While HLA-B*15:02 genotype testing in Asian populations is recommended by several international prescribing guidelines, it is not subsidized by the Medicare Benefits Schedule in Australia.ObjectiveTo evaluate the cost-effectiveness of HLA-B*15:02 genotyping … Show more
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