Echocardiographic evaluation of the aortic root and mitral valve in children and adolescents with isolated pectus excavatum: Comparison with Marfan patients
“…Our data conflict with the findings from Seliem et al, 11 who also examined the aortic roots of patients with isolated pectus excavatum, controls, and patients with MFS. Similar to our findings, the study by Seliem et al found no significant difference in the absolute diameter of the aortic root between the pectus excavatum and control groups; the measurements in both groups were statistically smaller than in their group of patients with MFS.…”
Section: Commentcontrasting
confidence: 99%
“…When Seliem et al indexed the aortic root size to BSA, they found no difference between the pectus excavatum and the control groups; in fact, predictably, the indexed aortic root diameter was significantly lower in the MFS group than in the other 2 groups. 11 The method of indexing the aortic root diameter by dividing it by BSA is valid only if the relationship of that indexed value is linear and passes through the origin. However, this method has been found to be inversely and nonlinearly dependent on BSA.…”
Section: Commentmentioning
confidence: 99%
“…[4][5][6]9 Pectus excavatum is seen in two-thirds of patients with MFS or related connective tissue diseases. 9,10 Seliem et al 11 compared aortic root diameters indexed to body surface areas (BSAs) in patients with an "isolated" pectus excava-tum, those with MFS, and a healthy control population. They did not find a significant difference between the isolated pectus excavatum and healthy control groups.…”
Aortic root dilatation is more common in patients with pectus excavatum than in a control population. Echocardiographic screening may be useful in the identification of aortic root dilatation in patients with isolated pectus excavatum.
“…Our data conflict with the findings from Seliem et al, 11 who also examined the aortic roots of patients with isolated pectus excavatum, controls, and patients with MFS. Similar to our findings, the study by Seliem et al found no significant difference in the absolute diameter of the aortic root between the pectus excavatum and control groups; the measurements in both groups were statistically smaller than in their group of patients with MFS.…”
Section: Commentcontrasting
confidence: 99%
“…When Seliem et al indexed the aortic root size to BSA, they found no difference between the pectus excavatum and the control groups; in fact, predictably, the indexed aortic root diameter was significantly lower in the MFS group than in the other 2 groups. 11 The method of indexing the aortic root diameter by dividing it by BSA is valid only if the relationship of that indexed value is linear and passes through the origin. However, this method has been found to be inversely and nonlinearly dependent on BSA.…”
Section: Commentmentioning
confidence: 99%
“…[4][5][6]9 Pectus excavatum is seen in two-thirds of patients with MFS or related connective tissue diseases. 9,10 Seliem et al 11 compared aortic root diameters indexed to body surface areas (BSAs) in patients with an "isolated" pectus excava-tum, those with MFS, and a healthy control population. They did not find a significant difference between the isolated pectus excavatum and healthy control groups.…”
Aortic root dilatation is more common in patients with pectus excavatum than in a control population. Echocardiographic screening may be useful in the identification of aortic root dilatation in patients with isolated pectus excavatum.
“…[3][4][5][6][7] It is difficult to prove, especially if the deformity is not severe. 5,[8][9][10] Although pectus excavatum is thought to impair mostly right ventricular performance, 9 the degree of right ventricular dysfunction, if any, produced by this chest wall deformity remains controversial. 5,11 The subjective physical improvement after the operation usually is not explained by changes in cardiorespiratory function.…”
Surgical treatment of funnel chest causes an increase in right ventricular systolic, diastolic, and stroke volumes, although there is no correlation between these changes and the degree of sternocostal elevation.
This study revealed that pectus excavatum leads to cardiac and pulmonary problems, and functions of the left ventricle may be affected by the deformity. Furthermore, the relation between the severity of the deformity and cardiovascular function is evident.
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