Chi-Lun Chang, Yu-Ju Chen, Carlo Giovanni Quintanilla, Ting-Sung Hsieh, Jen Liou
Abstract:STIM1 activates store-operated Ca2+ entry (SOCE) by translocating to endoplasmic reticulum–plasma membrane junctions. Chang et al. reveal that STIM1 localization and SOCE are regulated by a dynamic trapping mechanism mediated by STIM1 binding to EB1 at growing microtubule ends.
scite is a Brooklyn-based startup that helps researchers better discover and evaluate scientific articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by researchers from dozens of countries and is funded in part by the National Science Foundation and the National Institute of Drug Abuse of the National Institutes of Health.