Journal of Cell Biology volume 217, issue 6, P2047-2058 2018 DOI: 10.1083/jcb.201711151 View full text
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Chi-Lun Chang, Yu-Ju Chen, Carlo Giovanni Quintanilla, Ting-Sung Hsieh, Jen Liou

Abstract: STIM1 activates store-operated Ca2+ entry (SOCE) by translocating to endoplasmic reticulum–plasma membrane junctions. Chang et al. reveal that STIM1 localization and SOCE are regulated by a dynamic trapping mechanism mediated by STIM1 binding to EB1 at growing microtubule ends.