2005
DOI: 10.1016/j.ejcts.2005.07.005
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Fibrinolytic agents are a useful adjunct in the management of complicated parapneumonic effusions. Intrapleural fibrinolytics, if used early in the fibrinopurulent stage of a parapneumonic effusion, decrease the rate of surgical interventions (VATS or open decortcation) and the length of hospital stay with minor associated morbidity.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

2
70
1
7

Year Published

2006
2006
2021
2021

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 105 publications
(80 citation statements)
references
References 16 publications
2
70
1
7
Order By: Relevance
“…Hence, the fibrinolytic agent can be applied for improvement of drainage. A series studies also considered that the streptokinase or urokinase used in the pleural cavity can reduce hospital stay, prognosis improvement (9,(47)(48)(49)(50)(51) and prevent catastrophic hazards (4,50,52,53). However, the largest random and controlled clinical study considers that streptokinase application in the pleural cavity has failed to improve hospital stay, death rate and others, to date (22) and a researcher also considers that the fibrinolytic agent has failed to reduce fatality rate (54).…”
Section: Intrapleural Cavity Injectionmentioning
confidence: 99%
“…Hence, the fibrinolytic agent can be applied for improvement of drainage. A series studies also considered that the streptokinase or urokinase used in the pleural cavity can reduce hospital stay, prognosis improvement (9,(47)(48)(49)(50)(51) and prevent catastrophic hazards (4,50,52,53). However, the largest random and controlled clinical study considers that streptokinase application in the pleural cavity has failed to improve hospital stay, death rate and others, to date (22) and a researcher also considers that the fibrinolytic agent has failed to reduce fatality rate (54).…”
Section: Intrapleural Cavity Injectionmentioning
confidence: 99%
“…The families usually end-up spending all their meager resources on consultations and prolonged courses of expensive broad spectrum antibiotics far more than the cost of adequate treatment in a hospital. Misthos et al [8] in their study reported fever as the most common presenting symptom (88%) followed by cough (73%). We also observed fever as the frequent symptom (85.77%) followed by cough (61, 78).…”
Section: Discussionmentioning
confidence: 99%
“…Em um estudo controlado amplo, os trombolíticos não mostraram eficácia no controle do DPP loculado e do empiema, quando comparados com tratamentos convencionais. (24) Estudos atuais têm sugerido a utilização de agente trombolítico na primeira semana após o diagnóstico das septações, (25) com resultados animadores principalmente em pediatria. (26) Devemos também considerar que pacientes de alto risco operatório para o uso de anestesia geral podem se beneficiar da utilização alternativa dos trombolíticos.…”
Section: Agentes Trombolíticosunclassified
“…Um aumento importante do volume de líquido drenado após a instilação do trombolítico é um dos sinais mais importantes que sugerem ação na lise das loculações. (25)(26) Febre, calafrios e reações alérgicas podem ser relatados com a utilização da estreptoquinase, porém complicações mais sérias como sangramento pleural, fibrilação ventricular e insuficiência respiratória aguda são raras. (27) Os trombolíticos administrados no espaço pleural não alteram a coagulação sistêmica, sendo considerados drogas seguras para a prática clínica.…”
Section: Agentes Trombolíticosunclassified