Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome

Early rescue administration of surfactant and nasal continuous positive airway pressure in preterm infants <32 weeks gestation

“…Moreover, the incidence of pneumothorax and pulmonary emphysema air leak syndromes is very low in our study (0.7%) which is an expected result of elimination of mechanical ventilation. These findings are in accordance with trials reporting on improvement of gas exchange and the severity of RDS as well as for air leak syndromes after prophylactic surfactant compared with rescue therapy [17].…”

Early rescue administration of surfactant and nasal continuous positive airway pressure in preterm infants <32 weeks gestation

“…Moreover, the incidence of pneumothorax and pulmonary emphysema air leak syndromes is very low in our study (0.7%) which is an expected result of elimination of mechanical ventilation. These findings are in accordance with trials reporting on improvement of gas exchange and the severity of RDS as well as for air leak syndromes after prophylactic surfactant compared with rescue therapy [17].…”

Ten-year trend of care practices, morbidities and survival of very preterm neonates in the Malaysian National Neonatal Registry: a retrospective cohort study

“…Our result confirms a recent WHO study24 that ANS improves mortality of VPTN in LMICs like those in HICs 12 13. Similarly, we found the use of eCPAP14 and surfactant therapy25 26 were associated with better survival. MSAH16 was a predictor of mortality…”

Effect of Surfactant therapy on clinical outcome of Respiratory Distress Syndrome in premature neonates at French Medical Institute for Mother and Children

“…Study showed that the duration of hospitalization and adverse outcomes of preterm neonates with RDS treated with early intubation and surfactant administration were not significantly different with patients treated with routine protocol. In a systematic review, Stevens et al concluded that the frequency of MV dependency, BPD and air leak syndrome in a group of neonates treated with early surfactant therapy and NCPAP were less than a group treated with delayed surfactant therapy and MV, and this finding is similar to our findings [1]. We also found that birth weight, rate of ROP, and presence of lung bleeding could be associated with neonatal mortality seen in the MV group and is concordant with previous reports.…”

Early rescue administration of surfactant and nasal continuous positive airway pressure in preterm infants <32 weeks gestation

“…Moreover, the incidence of pneumothorax and pulmonary emphysema air leak syndromes is very low in our study (0.7%) which is an expected result of elimination of mechanical ventilation. These findings are in accordance with trials reporting on improvement of gas exchange and the severity of RDS as well as for air leak syndromes after prophylactic surfactant compared with rescue therapy [17].…”

Ten-year trend of care practices, morbidities and survival of very preterm neonates in the Malaysian National Neonatal Registry: a retrospective cohort study

“…Our result confirms a recent WHO study24 that ANS improves mortality of VPTN in LMICs like those in HICs 12 13. Similarly, we found the use of eCPAP14 and surfactant therapy25 26 were associated with better survival. MSAH16 was a predictor of mortality…”

Effect of Surfactant therapy on clinical outcome of Respiratory Distress Syndrome in premature neonates at French Medical Institute for Mother and Children

“…Study showed that the duration of hospitalization and adverse outcomes of preterm neonates with RDS treated with early intubation and surfactant administration were not significantly different with patients treated with routine protocol. In a systematic review, Stevens et al concluded that the frequency of MV dependency, BPD and air leak syndrome in a group of neonates treated with early surfactant therapy and NCPAP were less than a group treated with delayed surfactant therapy and MV, and this finding is similar to our findings [1]. We also found that birth weight, rate of ROP, and presence of lung bleeding could be associated with neonatal mortality seen in the MV group and is concordant with previous reports.…”

Early rescue administration of surfactant and nasal continuous positive airway pressure in preterm infants <32 weeks gestation

“…Moreover, the incidence of pneumothorax and pulmonary emphysema air leak syndromes is very low in our study (0.7%) which is an expected result of elimination of mechanical ventilation. These findings are in accordance with trials reporting on improvement of gas exchange and the severity of RDS as well as for air leak syndromes after prophylactic surfactant compared with rescue therapy [17].…”

Ten-year trend of care practices, morbidities and survival of very preterm neonates in the Malaysian National Neonatal Registry: a retrospective cohort study

“…Our result confirms a recent WHO study24 that ANS improves mortality of VPTN in LMICs like those in HICs 12 13. Similarly, we found the use of eCPAP14 and surfactant therapy25 26 were associated with better survival. MSAH16 was a predictor of mortality…”

Effect of Surfactant therapy on clinical outcome of Respiratory Distress Syndrome in premature neonates at French Medical Institute for Mother and Children

“…Study showed that the duration of hospitalization and adverse outcomes of preterm neonates with RDS treated with early intubation and surfactant administration were not significantly different with patients treated with routine protocol. In a systematic review, Stevens et al concluded that the frequency of MV dependency, BPD and air leak syndrome in a group of neonates treated with early surfactant therapy and NCPAP were less than a group treated with delayed surfactant therapy and MV, and this finding is similar to our findings [1]. We also found that birth weight, rate of ROP, and presence of lung bleeding could be associated with neonatal mortality seen in the MV group and is concordant with previous reports.…”