Early screening for critical congenital heart defects in asymptomatic newborns in Bursa province

Özalkaya, Elif; Akdag, Arzu; Şen, İsmai̇l; Cömert, Erol; Yaren, Hamide Melek

doi:10.3109/14767058.2015.1035642

Cited by 14 publications

(14 citation statements)

References 11 publications

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“…The prevalence of CCHD in our study was 6 of 1000 live births, with positive CCHD screens occurring in 8/1452 (0.6%) of newborns. This was higher than previously reported in Sri Lanka 0.16% (14/8718), [ 13 ], India 0.16% (3/1855) [ 12 ], Turkey 0.12% (12/10,200) [ 18 ], Morocco 0.06% (5/8013) [ 19 ], the Netherlands 0.02% (5/23,959) [ 20 ], New Zealand 0.02% (3/16,644) [ 21 ], South Africa 0.01% (1/1001) [ 11 ] and the United States (US) 0.01% (1/6745) [ 16 ].…”

Section: Discussionmentioning

confidence: 55%

Feasibility of screening for critical congenital heart disease using pulse oximetry in Indonesia

et al. 2022

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Background Screening of critical congenital heart disease (CCHD) using pulse oximetry is a routine procedure in many countries, but not in Indonesia. This study aimed to evaluate the feasibility of implementing CCHD screening with pulse oximetry for newborns in Yogyakarta, Indonesia. Methods A cross-sectional study was conducted at four hospitals in Yogyakarta, Indonesia. Newborns aged 24–48 hours who met the inclusion criteria were screened on the right hand and left or right foot using a pulse oximeter. Positive results were indicated by: either (1) SpO2 level < 90% in one extremity, (2) SpO2 level of 90–94% in both right hand and either foot on three measurements conducted 1 hour apart, or (3) a saturation difference > 3% between the upper and lower extremity on three measurements conducted 1 hour apart. Positive findings were confirmed by echocardiography. Results Of 1452 newborns eligible for screening, 10 had positive results and were referred for echocardiographic evaluation. Of those, 8 (6 per 1000 live birth, 8/1452) had CCHD. Barriers found during screening processes were associated with hospital procedures, equipment, healthcare personnel, and condition of the newborn. Conclusion Pulse oximetry screening might be feasible to be implemented within the routine newborn care setting for CCHD in Indonesia. In order to successfully implement pulse oximetry screening to identify CCHD in Indonesia, the barriers will need to be addressed.

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Section: Discussionmentioning

confidence: 55%

Feasibility of screening for critical congenital heart disease using pulse oximetry in Indonesia

et al. 2022

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“…Richmond et al 25 showed that repeat pulse oximetry brought their false positive rate down from 5% to 1%. In a local study from our country, Ozalkaya et al 26 reported the sensitivity and specificity of pulse oximetry screening in the diagnosis of CCHD as 60% and 99.9%, respectively. In the current study, sensitivity and specificity of the test were 83.3% and 99.9%, respectively.…”

Section: Discussionmentioning

confidence: 94%

Should we start a nationwide screening program for critical congenital heart disease in Turkey? A pilot study on four centres with different altitudes

Díllí

Doğan

Ozyurt³

et al. 2019

Cardiol Young

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Background:To investigate the feasibility of critical congenital heart disease (CCHD) screening test by pulse oximetry in four geographical regions of Turkey with different altitudes, before implementation of a nationwide screening program.Methods:It was a prospective multi-centre study performed in four centres, between December, 2015 and May, 2017. Pre- and post-ductal oxygen saturations and perfusion indices (PI) were measured using Masimo Radical-7 at early postnatal days. The results were evaluated according to the algorithm recommended by the American Academy of Pediatrics. Additionally, a PI value <0.7 was accepted to be significant.Results:In 4888 newborns, the mean screening time was 31.5 ± 12.1 hours. At first attempt, the mean values of pre- and post-ductal measurements were: saturation 97.3 ± 1.8%, PI 2.8 ± 2.0, versus saturation 97.7 ± 1.8%, PI 2.3±1.3, respectively. Pre-ductal saturations and PI and post-ductal saturations were the lowest in Centre 4 with the highest altitude. Overall test positivity rate was 0.85% (n = 42). CCHD was detected in six babies (0.12%). Of them, right hand (91 ± 6.3) and foot saturations (92.1 ± 4.3%) were lower compared to ones with non-CCHD and normal variants (p <0.05, for all comparisons). Sensitivity, specificity, positive and negative predictive values, and likelihood ratio of the test were: 83.3%, 99.9%, 11.9%, 99.9%, and 99.2%, respectively.Conclusion:This study concluded that pulse oximetry screening is an effective screening tool for congenital heart disease in newborns at different altitudes. We support the implementation of a national screening program with consideration of altitude differences for our country.

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“…Although it has not been introduced by the Ministry of Health as a mandatory screening program in our country, many centers from our country continue to share their screening results. Ozalkaya et al reported the sensitivity and specificity of pulse oximetry screening in the diagnosis of critical congenital heart defects as 60.0 % and 99.9%, respectively (17). In a prospective study by Dilli et al in which they shared data from centers of 4 different levels in our country, they determined a sensitivity of 83.3%, a specificity of 99.9%, a positive predictive value of 11.9%, and a negative predictive value of 99.9% (18).…”

Section: Discussionmentioning

confidence: 99%

Pulse Oximetry Screening Results at a Tertiary Care Center in Central-Antolia, Turkey

Yılmaz¹,

Emiroğlu²,

Oflaz³

et al. 2020

abantmedj

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Early screening for critical congenital heart defects in asymptomatic newborns in Bursa province

Abstract: The diagnosis of coarctation of the aorta is missed in the newborns screened with pulse oximetry in the first 24-48 h after birth. Screening with pulse oximetry should be repeated for early diagnosis of coarctation of the aorta.

Cited by 14 publications

References 11 publications

Feasibility of screening for critical congenital heart disease using pulse oximetry in Indonesia

Feasibility of screening for critical congenital heart disease using pulse oximetry in Indonesia

Should we start a nationwide screening program for critical congenital heart disease in Turkey? A pilot study on four centres with different altitudes

Pulse Oximetry Screening Results at a Tertiary Care Center in Central-Antolia, Turkey

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