Early Repolarization Pattern and Left Ventricular Mass in Hypertrophic Cardiomyopathy

Azevedo, Pedro; Guerreiro, Cláudio; Ladeiras-Lopes, Ricardo; Ferreira, Nuno; Faria, Rita; Barbosa, Raquel; Primo, João; Braga, Joana

doi:10.1159/000505639

Cited by 6 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…(2016) обнаружили, что у пациентов с псориазом ФРРЖ встречается чаще, чем у пациентов контрольной группы [31,39]. Нарушение проведения электрического импульса на фоне структурных, в том числе фиброзных, изменений миокарда -еще один механизм, сходный с FQRS, который может лежать в основе возникновения ФРРЖ [24,27,28,40,41]. Однако факт отсутствия ФРРЖ у пациентов с хроническим миокардитом без признаков воспаления позволяет предположить, что именно воспаление -наиболее значимый фактор в патогенезе ФРРЖ в изучаемой когорте пациентов.…”

Section: обсуждение результатовunclassified

Analysis of Fragmentation QRS Complex and Early Repolarization Pattern in Patients with Myocardial Inflammatory Changes

Gordeeva¹,

Serdiukova²,

Krasichkov³

et al. 2023

EPh

View full text Add to dashboard Cite

Inflammatory changes in the myocardium create the prerequisites for the electrical instability of the myocardium, which can affect the ECG. It is promising to study relatively new electrocardiographic patterns: fragmentation of QRS (FQRS) and premature ventricular beats (FPVB) and early repolarization pattern (ERP) to improve the screening of patients with suspected myocarditis. Aim. To study FQRS, FPVB and ERP in patients with inflammatory changes in the myocardium. Material and methods. The study included 46 patients (78.3% male, 21.7% women) with suspected myocarditis. Age: median 47.5, quartile 37; 56.5. In all patients, the anamnesis, results of ECG, echocardiography, cardiac magnetic resonance imaging and endomyocardial biopsy were analyzed. Results. The patients were divided into three groups: the 1st – 20 patients with inflammatory and fibrotic changes in the myocardium, the 2nd – 20 patients with myocardial fibrosis without inflammatory, the 3rd – 6 patients without structural changes in the myocardium. FQRS in the 1st group was detected in 35% of the examined, in the 2nd – in 25%, in the 3rd – not registered. FPVB in the 1st group was determined in 55% of the examined, in the 2nd – in 30%, in the 3rd – in 33.3%. ERP in the 1st group was registered in 30% of the examined, in the 2nd group it was not detected, in the 3rd group – in 16.7%. FPVB and ERP were informative for the detection of inflammation (sensitivity – 57.9 and 85% respectively, specificity – 69.2 and 53.8% respectively). For the detection of fibrosis, FPVB proved to be the most informative (sensitivity – 80.0%, specificity – 59.1%). Conclusions. FQRS, FPVB, and ERP are significant ECG-markers for detecting both inflammatory changes in the myocardium and fibrosis. The use of these ECG-markers in routine clinical practice may have an impact on further management of patients with suspected myocarditis.

show abstract

Section: обсуждение результатовunclassified

Analysis of Fragmentation QRS Complex and Early Repolarization Pattern in Patients with Myocardial Inflammatory Changes

Gordeeva¹,

Serdiukova²,

Krasichkov³

et al. 2023

EPh

View full text Add to dashboard Cite

show abstract

“…Larger LVEDV and LVM were observed in ERP+ patients, whereas the EF was smaller. The baseline parameters of the two groups were similar [ 65 ].…”

Section: Cardiac Morphofunctional Characteristics Of Individuals With...mentioning

confidence: 99%

Cardiac Morphofunctional Characteristics of Individuals with Early Repolarization Pattern: A Literature Review

Kocsis

Frigy

2022

JCDD

View full text Add to dashboard Cite

The early repolarization pattern (ERP) is an electrocardiographic phenomenon characterized by the appearance of a distinct J-wave or J-point elevation at the terminal part of the QRS complex. ERP is associated with an increased risk of ventricular arrhythmias in susceptible individuals. The cardiac morphofunctional parameters in subjects with ERP have been characterized mainly by imaging techniques, which suggests that certain changes could be identified in the background of the electrical pathomechanism: however, in this regard, current data are often contradictory or insufficiently detailed. For clarification a more comprehensive cardiac imaging evaluation of a large patient population for is necessary. This review summarizes and analyses the data from the literature related to cardiac morphofunctional characteristics in individuals with ERP.

show abstract

“…В исследованиях Nikoo M, et al (2020) и Bayramoğlu A, et al (2019г) было показано, что fQRS может быть предиктором снижения ФВ ЛЖ у здоровых лиц [35,36]. Наличие ФРРЖ также продемонстрировало взаимосвязь со структурными изменениями миокарда и с толщиной стенки ЛЖ [37][38][39]. Обнаружена высокая риск-стратификационная значимость ФРРЖ у пациентов со структурными изменениями миокарда различного генеза [40] как в общей популяции [41], так и при ХСН [42].…”

Section: Electrocardiographic Signs Of Impaired Depolarization (Fragm...unclassified

Electrocardiographic signs of impaired depolarization (fragmented QRS, early ventricular repolarization, etc.) as markers of left ventricular systolic dysfunction

et al. 2022

View full text Add to dashboard Cite

Aim. To study the relationship between a decrease in left ventricular (LV) ejection fraction (EF) and conventional electrocardiographic (ECG) signs associated with myocardial structure changes (pathological Q wave, ventricular arrhythmias), and relatively novel and less studied (fragmented QRS (fQRS), early ventricular repolarization (EVR)) and to evaluate their significance for identifying patients with mildly-reduced EF (mrEF).Material and methods. The study included 148 patients who were treated and examined at the Almazov National Medical Research Center. During the ECG analysis, fQRS, EVR, pathological Q wave, and ventricular arrhythmias (VAs) were assessed. Echocardiography data were analyzed. Statistical processing was carried out, including Fisher and chi-squared test, as well as correlation and ROC analysis.Results. Depending on the EF level, patients were divided into three groups: group 1 — patients with reduced EF (rEF) (<40%); group 2 — patients with mrEF (40-49%); group 3 — patients with preserved EF (pEF) (>50%). In the 1st group (with rEF), fQRS was registered in 16 (51,6%) patients, in the 2nd (with mrEF) — in 13 (44,8%), in the 3rd (with EF >50%) — in 16 (18,2%). Pathological Q wave was detected in the 1st group (rEF) in 20 (65%) patients, in the 2nd (mrEF) — in 10 (35%); in the 3rd (pEF) — in 15 (18%) (p<0,001). ROC analysis found that fQRS is more important for identifying patients with mrEF. In the 1st group (rEF), EVR was registered in 2 (6,5%) patients, in the 2nd (pEF) — in 2 (6,9%), in the 3rd (EF>50%) — in 11 (12,5%); the differences were not significant (p=0,5). The relationship of EVR, the number of PVCs and the presence of ventricular tachycardia with EF was not revealed.Conclusion. FQRS is significantly more often observed with a decrease in EF and may be a marker of an mildly-reduced EF. There were no significant correlations between EVR and EF. There was also no relationship between VAs and LV systolic dysfunction.

show abstract

Early Repolarization Pattern and Left Ventricular Mass in Hypertrophic Cardiomyopathy

Cited by 6 publications

References 15 publications

Analysis of Fragmentation QRS Complex and Early Repolarization Pattern in Patients with Myocardial Inflammatory Changes

Analysis of Fragmentation QRS Complex and Early Repolarization Pattern in Patients with Myocardial Inflammatory Changes

Cardiac Morphofunctional Characteristics of Individuals with Early Repolarization Pattern: A Literature Review

Electrocardiographic signs of impaired depolarization (fragmented QRS, early ventricular repolarization, etc.) as markers of left ventricular systolic dysfunction

Contact Info

Product

Resources

About