Early Recurrence After Pulmonary Vein Isolation of Paroxysmal Atrial Fibrillation With Different Ablation Technologies　– Prospective Comparison of Radiofrequency vs. Second-Generation Cryoballoon Ablation –

Pulmonary Vein Isolation Using a Second‐Generation Cryoballoon in Patients With Paroxysmal Atrial Fibrillation: One‐Year Outcome Using a Single Big‐Balloon 3‐Minute Freeze Technique

“…Our study showed that ERAFs were the sole significant factor for predicting AF recurrences after the blanking period, which was in agreement with the data post RF ablation . A prior study reported the greatest proportion of ERAFs in the first 2 weeks of the blanking period in a sample of patients fitted with an external loop recorder for the first 3 months after AF ablation using RF technology .…”

Transient manifestation of left ventricular diastolic dysfunction following ablation in patients with paroxysmal atrial fibrillation

“…However, Kenigsberg et al reported that the intact areas of the posterior LA wall immediately after PV isolation with CB ablation were only 27% . Myocardial damage during the procedure is reported to be larger in CB ablation than in RF ablation, which was also observed in our study. The edematous change during the acute phase might be greater in CB ablation than in RF ablation.…”

“…1 LA injury during the ablation procedure may be more severe in cryoballoon (CB) ablation than in radiofrequency (RF) ablation. 2 However, the immediate difference in LV diastolic function due to acutely impaired LA compliance between the 2 ablation procedures, possibly resulting from the extent of the isolated area of the posterior LA wall during the acute phase, remains to be seen. We recently reported afterloadrelated index for LV diastolic function is significantly higher in elderly (age ≥ 75 years) hypertensive females than in elderly hypertensive males.…”

“…Furthermore, the reduction in LA compliance after ablation may lead to relatively increased volume and elevation of left ventricular (LV) diastolic parameters . LA injury during the ablation procedure may be more severe in cryoballoon (CB) ablation than in radiofrequency (RF) ablation . However, the immediate difference in LV diastolic function due to acutely impaired LA compliance between the 2 ablation procedures, possibly resulting from the extent of the isolated area of the posterior LA wall during the acute phase, remains to be seen.…”

Mechanisms and clinical significance of early recurrences of atrial arrhythmias after catheter ablation for atrial fibrillation

“…In a nonrandomized fashion, Miyazaki et al[9] prospectively examined 82 consecutive patients with paroxysmal AF treated with PVI using either radiofrequency ablation vs cryoablation with the second generation cryoballoon. While the peak hs-CRP level was similar between ablation techniques, the level of hs-CRP 2 days post-ablation predicted development of ERAA in those treated with radiofrequency (HR = 1.7; 95%CI: 1.01-2.87; P = 0.048) but not cryoablation, suggesting that degree of inflammatory marker response may have a stronger predictive value for ERAA after radiofrequency compared with cryoablation.…”