Early rectal cancer: the European Association for Endoscopic Surgery (EAES) clinical consensus conference

Abstract

Background The last 30 years have witnessed a significant increase in the diagnosis of early stage

Treatment Interval between Neoadjuvant Chemoradiotherapy and Surgery in Rectal Cancer Patients: A Population-Based Study

“…Moreover, a reduction in the number of complications and permanent stomas might lead to a better functional outcome;12 however, these outcomes still have to be confirmed in randomized trials. Another drawback of the rectum-saving approach is that patients who need completion surgery will be overtreated with CRT, which has potential and serious side effects and long-term complications 7,14. It is therefore necessary that selection criteria of eligible patients be further explored prior to implementation.…”

Multicentre study of short-course radiotherapy and transanal endoscopic microsurgery for early rectal cancer

“…Transanal local excision alone can cure the majority of patients with early‐stage rectal cancer, with low complication rates, good postoperative bowel function and short hospital stay. However, in all but the very earliest cancers local relapse rates are substantially higher than those after primary TME surgery.…”

“…Transanal local excision alone can cure the majority of patients with early‐stage rectal cancer, with low complication rates, good postoperative bowel function and short hospital stay. However, in all but the very earliest cancers local relapse rates are substantially higher than those after primary TME surgery. External‐beam radiotherapy is used in conjunction with TEMS to help combat the risk of occult mesorectal lymph node metastasis and to downsize the primary tumour, thereby diminishing the risk of tumour implantation during local excision.…”

Robotic transanal microsurgery for high early rectal neoplasia (T0-T1, N0 lesions), case series of 10 patients

“…The six remaining cases had colonoscopic biopsy results concerning for malignancy including the two patients with biopsy results significant for invasive adenocarcinoma. With the exception of the distance from the anal verge, these six patients met the criteria for curative LE put forth in the 2014 EAES consensus statement and were considered low risk according to the National Comprehensive Cancer Network (NCCN) 2012 guidelines . Preoperative evaluation included CEA levels within normal limits, negative CT scans of the chest/abdomen/pelvis, and either pelvic MRI or endoscopic ultrasound which were all negative for evidence of significant depth of invasion and lymphadenopathy.…”