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Cited by 62 publications
(50 citation statements)
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“…[57][58][59] Anatomical factors also could interact considerably, as significant geometric changes are usually seen during RT, depending on the site: parotid gland shrinkage for example in HNC RT, with a higher initial volume and higher early volume changes as potential imaging biomarkers. [60][61][62] This shrinkage should be considered in terms of modelling predicted toxicity, as it could have complex structural and functional consequences leading to, e.g. xerostomia.…”
Section: Bjr|openmentioning
confidence: 99%
“…[57][58][59] Anatomical factors also could interact considerably, as significant geometric changes are usually seen during RT, depending on the site: parotid gland shrinkage for example in HNC RT, with a higher initial volume and higher early volume changes as potential imaging biomarkers. [60][61][62] This shrinkage should be considered in terms of modelling predicted toxicity, as it could have complex structural and functional consequences leading to, e.g. xerostomia.…”
Section: Bjr|openmentioning
confidence: 99%
“…Multiple manuscripts have been published using radiomics to predict radiation response, in some cases with prediction power outperforming standard clinical variables (77)(78)(79)(80)(81)(82), though not in all (83). Radiomicsbased statistical approaches can predict various radiation normal tissue complication probabilities including radiation pneumonitis, xerostomia, and rectal wall toxicity (84)(85)(86)(87)(88)(89). Radiomics data, coupled with genomic data and increasingly computable clinical record data, may escort radiation oncology into a new epoch of truly personalized radiation plans based on patient-specific knowledge.…”
Section: Tumor Control Probability and Normal Tissue Complication Promentioning
confidence: 99%
“…3 However, external radiotherapy of the parotid region is associated with many toxicities, including skin and auditory toxicity, xerostomia, and osteoradionecrosis. [4][5][6][7][8] Theoretically, most of these toxicities of parotid region could be minimized with the use of 125 I seed brachytherapy, with which it is possible to deliver high dose to the tumor volume while sparing surrounding tissue. 9,10 The aim of this retrospective study was to explore the efficacy and safety of surgery combined with postoperative 125 I seed brachytherapy for treatment of MEC of the parotid gland and to identify the factors influencing outcomes.…”
mentioning
confidence: 99%