Early postnatal (<96 hours) corticosteroids for preventing chronic lung disease in preterm infants

Late postnatal systemic steroids predispose to retinopathy of prematurity in very‐low‐birth‐weight infants: a comparative study

“…Contrary to these reports, Termote et al (24) showed that late hydrocortisone for BPD did not affect the incidence of severe ROP. In our study, late administration of steroids (a 5‐day course of betamethasone at 3–6 weeks of age) demonstrated the strongest association with development of ROP, thus conforming to results of previous studies in this regard (1–3,23).…”

Late postnatal systemic steroids predispose to retinopathy of prematurity in very‐low‐birth‐weight infants: a comparative study

“…Contrary to these reports, Termote et al (24) showed that late hydrocortisone for BPD did not affect the incidence of severe ROP. In our study, late administration of steroids (a 5‐day course of betamethasone at 3–6 weeks of age) demonstrated the strongest association with development of ROP, thus conforming to results of previous studies in this regard (1–3,23).…”

Postnatal glucocorticoids in preterm neonates: use in French neonatal centres in 2006

“…We found that corticosteroids are still frequently used in preterm infants in France, but only after the fourth day of life, to treat BPD and not as prevention therapy. We also found marginal use of dexamethasone, in accordance with reports of both short-term (digestive complaints, hyperglycaemia, arterial hypertension) and long-term (delayed growth affecting both height and weight, and neuropsychological development) adverse side effects2 – 5 suggesting an unbalanced benefit/risk ratio, despite its beneficial effect on respiratory status. In France, betamethasone is often used, as are inhaled steroids, in spite of the weak evidence base regarding its efficiency and long-term tolerance.…”

Vigabatrin therapy for infantile spasms: review of major trials in Europe, Canada, and the United States; and recommendations for dosing

“…Thus, initial treatment did not modify long‐term spasm control. In contrast to a previous report that suggested that giving steroids to young infants adversely impacts later neurodevelopment (36), there was no evidence of this occurrence in this study. Subsequently, an even longer term follow‐up of the UKISS patients was performed by Darke et al.…”

Late postnatal systemic steroids predispose to retinopathy of prematurity in very‐low‐birth‐weight infants: a comparative study

“…Contrary to these reports, Termote et al (24) showed that late hydrocortisone for BPD did not affect the incidence of severe ROP. In our study, late administration of steroids (a 5‐day course of betamethasone at 3–6 weeks of age) demonstrated the strongest association with development of ROP, thus conforming to results of previous studies in this regard (1–3,23).…”

Postnatal glucocorticoids in preterm neonates: use in French neonatal centres in 2006

“…We found that corticosteroids are still frequently used in preterm infants in France, but only after the fourth day of life, to treat BPD and not as prevention therapy. We also found marginal use of dexamethasone, in accordance with reports of both short-term (digestive complaints, hyperglycaemia, arterial hypertension) and long-term (delayed growth affecting both height and weight, and neuropsychological development) adverse side effects2 – 5 suggesting an unbalanced benefit/risk ratio, despite its beneficial effect on respiratory status. In France, betamethasone is often used, as are inhaled steroids, in spite of the weak evidence base regarding its efficiency and long-term tolerance.…”

Vigabatrin therapy for infantile spasms: review of major trials in Europe, Canada, and the United States; and recommendations for dosing

“…Thus, initial treatment did not modify long‐term spasm control. In contrast to a previous report that suggested that giving steroids to young infants adversely impacts later neurodevelopment (36), there was no evidence of this occurrence in this study. Subsequently, an even longer term follow‐up of the UKISS patients was performed by Darke et al.…”

Late postnatal systemic steroids predispose to retinopathy of prematurity in very‐low‐birth‐weight infants: a comparative study

“…Contrary to these reports, Termote et al (24) showed that late hydrocortisone for BPD did not affect the incidence of severe ROP. In our study, late administration of steroids (a 5‐day course of betamethasone at 3–6 weeks of age) demonstrated the strongest association with development of ROP, thus conforming to results of previous studies in this regard (1–3,23).…”

Postnatal glucocorticoids in preterm neonates: use in French neonatal centres in 2006

“…We found that corticosteroids are still frequently used in preterm infants in France, but only after the fourth day of life, to treat BPD and not as prevention therapy. We also found marginal use of dexamethasone, in accordance with reports of both short-term (digestive complaints, hyperglycaemia, arterial hypertension) and long-term (delayed growth affecting both height and weight, and neuropsychological development) adverse side effects2 – 5 suggesting an unbalanced benefit/risk ratio, despite its beneficial effect on respiratory status. In France, betamethasone is often used, as are inhaled steroids, in spite of the weak evidence base regarding its efficiency and long-term tolerance.…”

Vigabatrin therapy for infantile spasms: review of major trials in Europe, Canada, and the United States; and recommendations for dosing

“…Thus, initial treatment did not modify long‐term spasm control. In contrast to a previous report that suggested that giving steroids to young infants adversely impacts later neurodevelopment (36), there was no evidence of this occurrence in this study. Subsequently, an even longer term follow‐up of the UKISS patients was performed by Darke et al.…”