2013
DOI: 10.1183/09031936.00148712
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Abstract: The aim of this study was to describe the time patterns of wheezing in both asthmatic and nonasthmatic children during the first 36 months of life, and to determine whether there are asthma-related breakpoints in the incidence of wheezing.Data from a historical cohort of children followed from birth to 6 years (SLAM cohort) were used. Wheezing episodes until 36 months and asthma at 6 years were both recorded by a doctor. Monthly mean incidence rate of wheezing and rate ratio were calculated. Joinpoint regressi… Show more

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Cited by 15 publications
(9 citation statements)
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References 32 publications
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“…It is not shown whether the increase of episodes during early childhood is a protective factor with respect to adult asthma . Even the recent SLAM study confirms that there is still no effective method for distinguishing which breastfed babies with wheezing will later have asthma …”
Section: Discussionsupporting
confidence: 57%
See 1 more Smart Citation
“…It is not shown whether the increase of episodes during early childhood is a protective factor with respect to adult asthma . Even the recent SLAM study confirms that there is still no effective method for distinguishing which breastfed babies with wheezing will later have asthma …”
Section: Discussionsupporting
confidence: 57%
“…28,29 Even the recent SLAM study confirms that there is still no effective method for distinguishing which breastfed babies with wheezing will later have asthma. 30 Children who at 12 months of age were already attending a childcare centre were 2.12 times more likely to consult an emergency room, multiplying by 4 the risk of hospital admission. This increase in risk, although less pronounced, has been described previously 4 ; another study, 15 however, found no differences regarding hospital admissions.…”
Section: Discussionmentioning
confidence: 99%
“…Many wheezing infants have only a transient type of disease, however, approximately 40% of them will demonstrate asthma during school age. 2 Objective tools which could predict prognosis in these infants will assist in making the therapeutic decisions. 3 Tidal breath analysis (TBA) in wheezy infants, has been shown to predict subsequent wheezing illnesses.…”
Section: Introductionmentioning
confidence: 99%
“…Although it is known that asthma is influenced by age, sex, genetic background, and environmental exposure, the natural history of the disease is still poorly understood. The current knowledge about the evolution from wheeze in early childhood to asthma later on in life originates mainly from epidemiological studies (2)(3)(4)(5)(6)(7)(8). However, our understanding of the underlying pathophysiological mechanisms, particularly in the transition from childhood to adolescence, remains incomplete.…”
mentioning
confidence: 99%