2015
DOI: 10.1177/0269881115616383
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Abstract: . (2016). Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats. Journal of Psychopharmacology, 30 (2),[204][205][206][207][208][209][210][211][212][213][214] Early antipsychotic treatment in childhood/adolescent period has longterm effects on depressive-like, anxiety-like and locomotor behaviours in adult rats AbstractChildhood/adolescent antipsychotic drug (APD) use is exponentially increasing worldwide, desp… Show more

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Cited by 24 publications
(28 citation statements)
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“…Similarly, an increase in adult locomotor activity was reported with adolescent risperidone administration from PND22 to PND50 and this long-term motor outcome was observed only in males, not in females (De Santis et al 2016). …”
Section: Htsupporting
confidence: 53%
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“…Similarly, an increase in adult locomotor activity was reported with adolescent risperidone administration from PND22 to PND50 and this long-term motor outcome was observed only in males, not in females (De Santis et al 2016). …”
Section: Htsupporting
confidence: 53%
“…Adult rats with prior adolescent olanzapine or clozapine treatment did not show any impairment in either Morris Water Maze (MWM) test or elevated plus maze (EPM) Piontkewitz et al 2009). However, a recent study reported that adult rats treated with aripiprazole or risperidone treatment in adolescence spent longer time in the centre and the open part in EPM and these findings were selective to males (De Santis et al 2016). Reversal learning in T maze in adulthood was also not altered by chronic risperidone administration in juvenile and early-adolescent period (Bardgett et al 2013).…”
Section: Cognition Anxiety and Social Interactionmentioning
confidence: 91%
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