Dysplasia Surveillance in Inflammatory Bowel Disease

New Endoscopic and Diagnostic Techniques: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition: Management of GI Bleeding, Dysplasia Screening, and Endoscopic Training—Issues for the New Millennium

“…The studies emphasize the importance of initial screening because two patients already had developed carcinoma. Survival rates in patients with colorectal carcinomas detected as part of a surveillance program exceed survival rates in hospitals without surveillance programs and in patients who elect not to participate in screening programs who develop colorectal carcinoma (5).…”

“…Hospital-based series using actuarial methods of analysis suggested risks as high as 9% to 42% after 25 years of disease. Population-based series suggest the risk of developing adenocarcinoma is 3% to 10% at 25 years in patients with universal colitis (5). The risk of developing cancer is highest in individuals with extensive large bowel disease, and seems to rise after 8 to 10 years of disease.…”