Dyslipidaemia as a risk factor in the occurrence of stroke in Nigeria: prevalence and patterns

Olamoyegun, Michael Adeyemi; Akinlade, Akinyele; Fawale, Bimbo; Ogbera, Anthonia O

doi:10.11604/pamj.2016.25.72.6496

Cited by 33 publications

(30 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Africa (18.5%) [9]. Unlike many previous studies [22,30,38,[42][43][44][45], low HDL-C is the least prevalent component of dyslipidemia in this study. Advanced age, higher BMI, waking less than 150 minutes per week, raised FBG, and medium socio-economic status were significantly associated with a higher risk of dyslipidemia.…”

Section: Plos Onecontrasting

confidence: 66%

Prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City, Northern Ethiopia

et al. 2021

View full text Add to dashboard Cite

Introduction Dyslipidemia is a major risk factor for cardiovascular diseases (CVD). The prevalence of dyslipidemia is not known among Ethiopian adults. The prevalence is expected to rise due to the socio-economic development accompanied by lifestyle changes. This study was conducted to estimate the prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City. Methods A community-based cross-sectional study was conducted among 321 randomly selected subjects. Data were collected on sociodemographic, anthropometric, lifestyle, and clinical characteristics of the participants using the WHO STEPS survey instrument. Data were analyzed using SPSS software version 24.0. Student’s t-test and Pearson’s Chi-square test were used to assessing the interrelationship between each factor and outcome variables. Bivariate and multivariable logistic regression analysis were used to identify risk factors associated with dyslipidemia. All statistical significance was considered at p ≤0.05. Results The prevalence of dyslipidemia in this study was 66.7%. The prevalence of high low-density lipoprotein cholesterol (LDL-C), elevated triglyceride, elevated total cholesterol, and low high-density lipoprotein cholesterol (HDL-C) was 49.5%, 40.2%, 30.8%, and 16.5%, respectively. Being above 64 years (aOR: 2.196, 95% CI: 1.183–4.078) and 40–64 years old (aOR: 2.196, 95% CI: 1.183–4.078), overweight (aOR: 2.50, 95% CI: 1.314–4.756) and obesity (aOR: 15.489, 95% CI: 3.525–68.070), walking <150 minutes per week (aOR: 1.722, 95% CI: 1.004–2.953), raised fasting blood glucose (FBG) (aOR: 4.804, 95% CI: 1.925–11.988), and medium socio-economic status (aOR: 2.017, 95% CI: 1.044–3.899) were identified as significant predictors of dyslipidemia. Conclusions The finding of this study indicated that the prevalence of dyslipidemia is unacceptably high among adult residents of Mekelle City, which underlines an urgent need for early detection and public health interventions through the integrated involvement of public, governmental, and non-governmental organizations.

show abstract

Section: Plos Onecontrasting

confidence: 66%

Prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City, Northern Ethiopia

et al. 2021

View full text Add to dashboard Cite

show abstract

“…This finding is however in variance with other studies done among patients with diabetes2021 but similar to a study by Anyawu et al . and Olamoyegun et al ., who looked at endocrine-related disorders presenting to the Emergency in Lagos, Nigeria, and dyslipidemia in Nigerians, respectively 422. The higher percentage of patients with diabetes in our study (68.7%) is in keeping with other studies.…”

Section: Discussionsupporting

confidence: 90%

Patterns and Impact of Consultations to an Endocrinology Unit in a Tertiary Hospital in Southwestern Nigeria

et al. 2018

View full text Add to dashboard Cite

Background: The dearth of endocrinologists in Nigeria, coupled with a paucity of data on patterns of endocrine consultations pose a challenge in evaluating the impact of consultations on patients' management and eventual outcomes. The objectives of this study were to determine the frequency, sources of referrals, the common cases referred, the reasons for consultation requests, and the outcome of patients who benefitted from endocrine consultations. Materials and Methods: This study was carried out in the Endocrinology unit of Babcock University Teaching Hospital, over 9 months. All patients referred to the unit were sampled (total sampling). Their sociodemographic parameters, sources, and reasons for consultations were documented. The patients' case notes were then retrospectively reviewed, to determine the impact of the consultation on their management and outcome. Results: A total of 108 consults were received throughout the study. Most consultations were requested by the general outpatient clinic (37%) followed by cardiology clinic (12%). The most common reason was to take over management of the patients. Diabetes mellitus accounted for 68.7% of the cases seen. Diagnosis made by the referring physician was confirmed in most cases, new diagnoses or change in diagnosis was reached in 9.3% and 3.7%, respectively. About 39.8% of the patients were lost to follow-up, while 53.8% were in good and fair clinical condition. Conclusion: Most of the cases referred for specialist care were from the general outpatient clinic, had diabetes mellitus, and benefitted from specialist care by the way of advanced investigations and treatments, though about a third were lost to follow-up. It is imperative that a good referral system is maintained among physicians, to ensure that patients get the best care available. Attention must be paid to common causes of patient attrition such as lack of widespread health insurance coverage, to ensure continuity of care.

show abstract

“…Diabetes mellitus had obvious impact on the lipids, which mainly reflects in the rise of Triglyceride (TG) and fall of High density lipoprotein cholesterol (HDL-C) [ 6 , 7 ]. Both the blood glucose and lipids would play the important role on the occurrence of arteriosclerosis, while lipids would play the more direct role [ 8 , 9 ]. Did this mean that the induction of arteriosclerosis and ischemic stroke by DM was through lipids, and this was proved in our previous study, that was, low level of HDL-C was correlated to the occurrence of AIS induced by DM [ 10 ], which demonstrated that dyslipidaemia was prone to happening in the AIS with DM.…”

Section: Introductionmentioning

confidence: 99%

Dyslipidaemia was correlated to the posterior circulation infarction in non-diabetic populations

Luo

Zhang

et al. 2018

Lipids Health Dis

View full text Add to dashboard Cite

BackgroundDiabetes mellitus (DM) was prone to happening in posterior circulation infarction (POCI) and DM also has the impact on the lipids, our study was to investigate the correlation between lipid compositions and POCI.MethodsData was collected from the patients with acute ischemic stroke (AIS) hospitalization in Affiliated Drum Tower Hospital of Nanjing University Medical School from October 2008 to May 2012. Lipids and other risk factors in the different populations were investigated in relation to occurrence of POCI based on the infarction location.ResultsSix hundred ten patients with AIS were included in this study, which had 428 with anterior circulation infarction (ACI) and 182 with POCI. Elevated Triglyceride (TG) and decreased High density lipoprotein cholesterol (HDL-C) were seen in the POCI of total populations and AIS without DM compared to the ACI, but not in the populations of AIS with DM, so did the elevated TG/HDL-C ratios. Also, the percent of low HDL-C level and high TG level were higher in POCI group than that in ACI group. Furthermore, single factors logistic regression demonstrated that TG, HDL-C and TG/HDL-C ratio were correlated to the POCI whatever in the total populations or AIS without DM, but this kind of trend just maintained in the populations of AIS without DM after adjusting by relative interference factors.ConclusionDyslipidaemia was prone to happening in POCI compared to ACI in the non-diabetic populations, which was correlated to the pathogenesis of POCI.

show abstract

Dyslipidaemia as a risk factor in the occurrence of stroke in Nigeria: prevalence and patterns

Cited by 33 publications

References 25 publications

Prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City, Northern Ethiopia

Prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City, Northern Ethiopia

Patterns and Impact of Consultations to an Endocrinology Unit in a Tertiary Hospital in Southwestern Nigeria

Dyslipidaemia was correlated to the posterior circulation infarction in non-diabetic populations

Contact Info

Product

Resources

About