DOI: 10.31219/osf.io/vfz4t
View full text
Johannes Jaeger, Nick Monk

Abstract: An organism’s phenotype can be thought of as consisting of a set of discrete traits, able to evolve relatively independently of each other. This implies that the developmental processes generating these traits—the underlying genotype-phenotype map—must also be functionally organised in a modular manner. The genotype-phenotype map lies at the heart of evolutionary systems biology. Recently, it has become popular to define developmental modules in terms of the structure of gene regulatory networks. This approach…

expand abstract