Dynamic Relations Between Psychological Resilience and Post-Concussion Symptoms in Children With Mild Traumatic Brain Injury Versus Orthopedic Injury: An A-CAP Study

Hassan, Abul; Brooks, Brian L.; McArthur, Brae Anne; Beauchamp, Miriam H.; Craig, William; Doan, Quynh; Zemek, Roger; Yeates, Keith Owen

doi:10.1089/neu.2023.0014

Cited by 4 publications

(1 citation statement)

References 44 publications

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“…These findings are related to studies on the relationship between trait resilience (arguably the opposite of pain catastrophizing) and concussion outcomes. Reduced resilience is linked to increased symptoms and a prolonged recovery from SRCs, whereas high resilience shows the opposite [178,179].…”

Section: Pain Catastrophizingmentioning

confidence: 99%

Conservative Management of Acute Sports-Related Concussions: A Narrative Review

Kureshi,

Mendizabal,

Francis

et al. 2024

Healthcare

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This review explores the application of the conservative management model for pain to sports-related concussions (SRCs), framing concussions as a distinct form of pain syndrome with a pathophysiological foundation in central sensitization. Drawing parallels with proven pain management models, we underscore the significance of a proactive approach to concussion management. Recognizing concussions as a pain syndrome allows for the tailoring of interventions in alignment with conservative principles. This review first covers the epidemiology and controversies surrounding prolonged concussion recovery and persistent post-concussion symptoms (PPCS). Next, the pathophysiology of concussions is presented within the central sensitization framework, emphasizing the need for early intervention to mitigate the neuroplastic changes that lead to heightened pain sensitivity. Five components of the central sensitization process specific to concussion injuries are highlighted as targets for conservative interventions in the acute period: peripheral sensitization, cerebral metabolic dysfunction, neuroinflammation, glymphatic system dysfunction, and pain catastrophizing. These proactive interventions are emphasized as pivotal in accelerating concussion recovery and reducing the risk of prolonged symptoms and PPCS, in line with the philosophy of conservative management.

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Section: Pain Catastrophizingmentioning

confidence: 99%

Conservative Management of Acute Sports-Related Concussions: A Narrative Review

Kureshi,

Mendizabal,

Francis

et al. 2024

Healthcare

View full text Add to dashboard Cite

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Associations Between Changes in Psychological Resilience and Resting-State Functional Connectivity Throughout Pediatric Concussion Recovery

Brown,

Fang,

Smith

et al. 2024

Brain Connectivity

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This study investigated the association between psychological resilience and resting-state network functional connectivity in pediatric concussion. MethodsThis was a substudy of a randomized controlled trial, recruiting children with concussion and orthopedic injury. Participants completed the Connor-Davidson Resilience 10 Scale and underwent magnetic resonance imaging at 72 hours and 4-weeks post-injury. Seed-to-voxel analyses were used to explore associations between resilience and connectivity with the default-mode, central executive, and salience networks longitudinally and at both timepoints separately. Regions-of-interest analyses were used to explore associations between resilience and within-network connectivity. ResultsA total of 69 children with a concussion ]; 46% female) and 30 with orthopedic injury ]; 40% female) were included. Seed-to-voxel analyses detected a positive correlation between 72-hour resilience and central executive network connectivity in the concussion group, and a positive correlation between 72-hour resilience and salience network connectivity in the orthopedic injury group. Group was a moderator of 72-hour resilience and salience network connectivity, and a moderator of longitudinal resilience and default-mode network connectivity. Regions-of-interest analyses identi ed group as a moderator of longitudinal resilience and within-default-mode network connectivity. In the orthopedic injury group, longitudinal resilience was associated with within-default-mode network connectivity, while 72-hour resilience was associated with within-salience network connectivity. ConclusionsThese results suggest that resilience may be implicated in functional neuroimaging outcomes in pediatric concussion and should further be investigated for its clinical utility as a protective or restorative factor following injury. This is a secondary analysis of a larger randomized clinical trial, Pediatric Concussion Assessment of Rest and Exertion (PedCARE;Ledoux et al., 2019), where a subsample of children with a concussion or orthopedic injury underwent an MRI scan at 72hrs (+/-48hrs) and 4-weeks (+/-5 days) post-injury (Ledoux et al., 2019).Click or tap here to enter text. This study received approval by the Research Ethic Board and the Children's Hospital of Eastern Ontario. All eligible children and adolescents capable of consenting on their own behalf provided written informed consent, while those unable to consent on their own behalf provided assent and parental consent. ParticipantsChildren with a concussion or an orthopedic injury (OI) were included in the study if they sustained a concussion or OI < 48hrs from their emergency department visit, were 10 to 17.99 years of age, and pro cient in English. Concussion participants were excluded from the study if they presented with a Glasgow Coma Scale score of < = 13, had abnormalities on standard imaging, underwent intubation, or had a history of trauma prior to the injury. Children with an orthopedic injury were excluded if their injury was isolated to the ...

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