2016
DOI: 10.1097/wnr.0000000000000534 View full text |Buy / Rent full text
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Abstract: Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment tool for the recovery of cerebral palsy (CP). This report describes the modulation effect of rTMS to functional connectivity, functional network connectivity, motor, and cognitive ability following treatment in a child with mild ataxia CP. After receiving 8 months of 0.5 Hz rTMS treatment over the right dorsolateral prefrontal cortex, the child showed a gradual improvement in motor and cognitive-related functional connectivity and f… Show more

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“…However, these differences were not statistically significant, which may be due to the small number of patients included, and impaired brain structure of the children with CP. Although the mechanism of combining tDCS and cognitive training together is not proved yet, tDCS stimulating the DLPFC, which is the main cortex related with working memory ( 32 ), may excite the cognitive process and functional connectivity in the brain, as shown in a previous study ( 33 ) of TMS in children with CP. Accordingly, tDCS may maximize the effect of cognitive training of children with CP.…”
Section: Discussionmentioning
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“…However, these differences were not statistically significant, which may be due to the small number of patients included, and impaired brain structure of the children with CP. Although the mechanism of combining tDCS and cognitive training together is not proved yet, tDCS stimulating the DLPFC, which is the main cortex related with working memory ( 32 ), may excite the cognitive process and functional connectivity in the brain, as shown in a previous study ( 33 ) of TMS in children with CP. Accordingly, tDCS may maximize the effect of cognitive training of children with CP.…”
Section: Discussionmentioning
“…[32] In addition, rTMS treatment of CP patients demonstrated improvement both in the motor and cognitive functions due to increased functional connectivity and network of the neurons. [33] Moreover, a good number of evidence have accumulated showing that rTMS can modulate neuronal networks to improve motor functions in patients suffering from stroke, multiple sclerosis, and CP. [93435]…”
Section: Discussionmentioning
“…While most of the studies measured only motor performance as the outcome, the study by Dadashi et al also documented improvement in balance control [93]. One case report and one controlled trial assessed the effect of rTMS on cognitive performance in CP [94,95]. In the first, the right DLPFC was stimulated with low -0.5 Hz, and in the second the left DLPFC with high -10 Hz, frequency.…”
Section: Repetitive Transcranial Magnetic Stimulation As a Therapeutic Tool In Cerebral Palsymentioning