Ilze Skujina, Robert McMahon, Vasileios Panagiotis E. Lenis, Georgios V. Gkoutos, Matthew Hegarty
Abstract:Despite a number of biochemical and lifestyle differences which should increase risk of oxidative damage to their mitochondrial DNA (mtDNA) and thus reduce expected lifespan, avian species often display longer lifespans than mammals of similar body mass. Recent work in mammalian ageing has demonstrated that functional mitochondrial copy number declines with age. We noted that several bird species display duplication of the control region (CR) of the mtDNA to form a pseudo-control region (YCR), apparently an av…
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