Duplication and subsequent functional diversification of aquaporin family in Pacific abalone Haliotis discus hannai

Jia, Yanglei; Xu, Fei; Xiao, Lianchun

doi:10.1016/j.ympev.2022.107392

Cited by 4 publications

(2 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, similar permeation properties were not detected in molluscs. For instance, previous research revealed that although these replacements enlarged the diameter of the AQP ortholog in Pacific abalone, it was still not capable of mediating the permeation of glycerol [ 40 ]. Besides, similar orthologs in terrestrial snail Helix pomatia could stimulate the permeation of hydrogen peroxide but is not permeable to glycerol [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

“…Remarkably, some AQPs with the similar composition pattern of the Ar/R region to that in Mglp also appeared in holometabolan insects to compensate for the absence of Glp subfamily in these species [ 26 ]. Previous research has revealed that the Mglps in Pacific abalone were derived from tandem duplication and subsequent functional differentiation [ 40 ]. However, similar phenomenon was not detected between the tandem duplicated AQP orthologs in oysters, although the Glp subfamily in these species were extremely contracted.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Diversification of the aquaporin family in geographical isolated oyster species promote the adaptability to dynamic environments

Jia

Liu

2022

BMC Genomics

Self Cite

View full text Add to dashboard Cite

Background The diversified aquaporin (AQP) family that was derived from gene duplication and subsequent functional differentiation play critical roles in multiple physiological processes and in adaptation to the dynamic environments during the evolutionary process. Oysters are a group of bivalve fauna in Mollusca that were widely distributed around the world and show extraordinary adaptation to harsh environments. However, knowledge is lacking with the diversity and evolution of the AQP family in oysters, even in molluscs. Results Here, we performed a comprehensive analysis of the AQP family in three geographical isolated oyster species that are native to different environments. Genome distribution and phylogenetic analysis revealed that the expansion of the AQP family in oysters were attributed to tandem duplication. Synteny analysis indicated that large-scale inversions lead to the independent duplication or deletion of the AQPs after speciation. As a consequence, these independent duplication events contributed to the diversification of the AQP family in different oysters. Pore pattern analysis suggested that the duplicated AQPs in oysters were highly diversified in inner surface profiles, implying the subsequent functional differentiation. The comparison conducted based on the transcriptome data demonstrated that the functional differentiated AQP family members in oysters may play critical roles in maintaining the balance between the stationary homeostasis and dynamic environments. Conclusions Our observation provides evidence for the correlation between the duplicated and functional differentiated AQP family and the adaptation to stationary life under dynamic environments in oysters. Additionally, it also broadens our knowledge of the evolution of AQP family in molluscs.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Diversification of the aquaporin family in geographical isolated oyster species promote the adaptability to dynamic environments

Jia

Liu

2022

BMC Genomics

Self Cite

View full text Add to dashboard Cite

show abstract

Artemia enrichment as modulator of gene expression patterns of Enteroctopus megalocyathus paralarvae at pre-settlement stage

Uriarte,

Enríquez,

Hernández

et al. 2024

Aquaculture

View full text Add to dashboard Cite

Genome-wide identification, structural and evolutionary characteristics, and expression analysis of aquaporin gene family members in Mercenaria mercenaria

Zhou

Lin²,

She³

et al. 2023

Front. Mar. Sci.

View full text Add to dashboard Cite

Aquaporins (AQPs) are highly-selective transmembrane water transporters that are involved in the adaptation to environmental challenges. However, the structure, function, and evolution of AQPs in bivalves remain largely unknown. In this study, AQP gene family members were identified in nine bivalve species, and their abundance rangs from 7 to 15. Nine AQPs (MmAQPs) were identified in the genome of hard clam (Mercenaria mercenaria), which is a euryhaline bivalve that has evolved sophisticated osmoregulatory mechanisms and salinity adaptation. Structurally, all MmAQPs contain 6 or 12 transmembrane α-helices, a major intrinsic protein (MIP) domain, and 2 asparagine-proline-alanine (NPA) motifs. MmAQPs were classified into three subfamilies based on phylogenetic analysis: AQP1-like, AQP3-like, and AQP8-like. No AQP11-like subfamily member was identified in the genome of hard clam. Tandem duplication resulted in a lineage-specific expansion in AQP8-like subfamily in hard clams. MmAQP8 genes showed different expression sensitivity to different environmental stressors. The gene expression patterns of three MmAQP8 were similar under heat, hypoxia, and air exposure stress, but differed greatly under salinity stress, indicating that tandem duplication events may accelerate the functional divergence of AQP8 genes in hard clams. AQP3-like members may have undergone gene loss during evolution, resulting in weakened glycerol and urea penetration in hard clams. Three orthologs of MmAQPs were detected in the genomes of Cyclina sinensis and Archivesica marissinica through synteny analyses. Tissue expression profiles showed that MmAQP genes were highly expressed in the foot and hepatopancreas. Under environmental stress, the expression levels of most of the MmAQP genes changed significantly to maintain metabolic homeostasis. Several MmAQP genes were downregulated to reduce water permeability under salinity and air exposure stress. Several MmAQP genes were significantly upregulated to promote the transmembrane transport of ammonia and reactive oxygen species and activate anti-apoptotic responses to resist stress. This study provides a comprehensive understanding of the AQP gene family in hard clams, and lays a foundation for further studies to explore the functions of AQPs in bivalves.

show abstract

Duplication and subsequent functional diversification of aquaporin family in Pacific abalone Haliotis discus hannai

Cited by 4 publications

References 76 publications

Diversification of the aquaporin family in geographical isolated oyster species promote the adaptability to dynamic environments

Diversification of the aquaporin family in geographical isolated oyster species promote the adaptability to dynamic environments

Artemia enrichment as modulator of gene expression patterns of Enteroctopus megalocyathus paralarvae at pre-settlement stage

Genome-wide identification, structural and evolutionary characteristics, and expression analysis of aquaporin gene family members in Mercenaria mercenaria

Contact Info

Product

Resources

About