Dual-signal sandwich electrochemical immunosensor for amyloid β-protein detection based on Cu–Al2O3-g–C3N4–Pd and UiO-66@PANI-MB

Miao, Juncong; Li, Xuan; Li, Yueyuan; Duan, Xue; Zhao, Guanhui; Fang, Jinglong; Wei, Qin; Cao, Wei

doi:10.1016/j.aca.2019.09.017

Cited by 31 publications

(27 citation statements)

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“…The sensor also utilizes a square wave voltammetry signal while using a current ampere I-t curve signal.UiO-66@PANI-MB as a signal tag compared to UiO-66 helps stabilize electrode structure and increase electron transfer rate. The dual-signal mode improves the analytical performance of electrochemical immunosensor and is vital for the prediagnosis of Alzheimer’s disease ( Miao et al, 2019 ).…”

Section: Application Of Uio-66-based Electrochemical Biosensorsmentioning

confidence: 99%

Research Progress of UiO-66-Based Electrochemical Biosensors

Zhang

et al. 2022

Front. Chem.

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UiO-66, as a member of the MOFs families, is widely employed in sensing, drug release, separation, and adsorption due to its large specific surface area, uniform pore size, easy functionalization, and excellent stability. Especially in electrochemical biosensors, UiO-66 has demonstrated excellent adsorption capacity and response signal, which significantly improves the sensitivity and specificity of detection. However, the existing application research remains in its infancy, lacking systematic methods, and recycling utilization and exclusive sensing of UiO-66 still require further improvement. Therefore, one of the present research objectives is to explore the breakthrough point of existing technologies and optimize the performance of UiO-66-based electrochemical biosensors (UiO-66-EBs). In this work, we summarized current experimental methods and detection mechanisms of UiO-66-EBs in environmental detection, food safety, and disease diagnosis, analyzed the existing problems, and proposed some suggestions to provide new ideas for future research.

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Section: Application Of Uio-66-based Electrochemical Biosensorsmentioning

confidence: 99%

Research Progress of UiO-66-Based Electrochemical Biosensors

Zhang

et al. 2022

Front. Chem.

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“…g‐C 3 N 4 and its composites have begun to be applied in the study of inhibiting and detecting the polymerization of Aβ by virtue of good chemical stability, excellent physicochemical properties, and good visible light or activity [77–79] . Li et al [80] .…”

Section: G‐c3n4 In Disease Treatment and Monitoringmentioning

confidence: 99%

Graphite Carbon Nitride and Its Composites for Medicine and Health Applications

Zhang

Kan

et al. 2021

Chemistry An Asian Journal

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With the progress of science and technology and the improvement of people‘s living standards, the performance of traditional materials can no longer fully meet the needs of social development. Graphitic phase carbon nitride (g‐C3N4), as a new type of nanomaterial, has good properties. Its unique graphite like structure and stable thermodynamic characteristics have led an increasing number of researchers to explore its diverse functions and use this as a basis to develop related energy and products for applications in various fields. Among them, applications in the field of medicine health have become popular in recent years. Therefore, this review summarizes the synthesis methods of g‐C3N4 and its composites, as well as their applications in food, medicine, environmental monitoring and disease treatment, in the hope of providing references and basis for further expanding the applications of g‐C3N4 in large health areas.

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“…One of the critical steps in the development of an electrochemical sensor is ensuring the transfer of the electrons involved in the reaction, from the sample to a sensor in a highly sensitive, accurate and repeatable manner. To this end, conducting polymer have been widely studied during the last decade along with making them suitable for biosensor applications [33] coupling it to enzymes [34][35][36], antibodies [37][38][39].…”

Section: Introductionmentioning

confidence: 99%