Dual-functional composite scaffolds for inhibiting infection and promoting bone regeneration

Application of bioactive metal ions in the treatment of bone defects

“…Bone tissue growth will be inhibited when infection occurs, and osteogenesis can only be performed after the infection is cured. 202,203 Therefore, implants that can prevent infection and promote bone tissue growth are ideal for infected bone defects. 204,205 There are many studies on the treatment of infectious bone defects with metal ions in BTE, and the carriers are similar to some of the BTE carriers mentioned above, including BGs, HA, CaP, PLGA, collagen, Ti, PCL, and other materials.…”

Recent advances in carbon dots: synthesis and applications in bone tissue engineering

“…Infected bone defects have long been a problematic issue in orthopedics, as infection can significantly impair local tissue and bone regeneration, making the defect difficult to heal. 116 Commonly used treatments include removal of necrotic bone, use of antibiotics and reconstruction of bone defects. However, these treatments are time-consuming and ineffective.…”

Magnetic Nanomaterials Mediate Electromagnetic Stimulations of Nerves for Applications in Stem Cell and Cancer Treatments

“…Orthopedic disorders, including infections, cancers, and bone loss, continue to represent problems in global public health [ 107 , 108 , 109 ]. As populations get older, this problem assumes additional significance because degenerative disorders, such as osteoporosis, can increase the likelihood of bone fractures and make it more challenging to mend broken bones.…”