DTPA Captopril Renogram: Still an Invaluable Tool for Probability Assessment in Suspected Cases of Renovascular Hypertension

Sultana, Nasreen; Begum, Shelina; Parveen, Rafia; Sarker, Azmal Kabir; Mutsuddy, Pupree; Islam, Saiful; Chaudhary, Amardeep

doi:10.3329/bjnm.v18i2.35220

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“…A stenosis greater than 75% in one or both renal arteries is considered significant [9]. Though not suitable for initial screening, captopril renogram may help to assess haemodynamic significance of the stenotic lesion and determine the relative function of each kidney [12].…”

Section: Familial Hyperaldosteronism <1%mentioning

confidence: 99%

Hypertension with Metabolic Alkalosis and Hypokalaemia– Could it be Aldosterone?

Jiang¹,

Castelino²,

Tarafdar³

2019

JCR

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Background: Hypertension has a worldwide prevalence of 31% and contributes markedly to death from stroke and coronary heart disease. Up to 10% of hypertensive patients have secondary hypertension; an even higher prevalence is present amongst patients below the age of 30. The two commonest causes of secondary hypertension, primary aldosteronism and renovascular disease, may both present with metabolic alkalosis and/ or hypokalaemia. While both conditions are associated with raised plasma aldosterone, plasma renin concentration is low in primary aldosteronism and high in renovascular hypertension, giving rise to the characteristically high plasma aldosterone concentration: plasma renin concentration (>30:1) in the former. Case Report: We hereby report two hypertensive cases who presented with metabolic alkalosis and/or hypokalaemia. The two common causes of secondary hypertension, namely primary aldosteronism (PA) and renovascular disease, are presented in this case series. Conclusion: Diagnosis of secondary cause of hypertension such as primary aldosteronism or renovascular disease leads to targeted anti-hypertensive therapy resulting in better patient management.

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Section: Familial Hyperaldosteronism <1%mentioning

confidence: 99%